| pubmed-article:19364742 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19364742 | lifeskim:mentions | umls-concept:C0026845 | lld:lifeskim |
| pubmed-article:19364742 | lifeskim:mentions | umls-concept:C0022702 | lld:lifeskim |
| pubmed-article:19364742 | lifeskim:mentions | umls-concept:C0450031 | lld:lifeskim |
| pubmed-article:19364742 | lifeskim:mentions | umls-concept:C2584313 | lld:lifeskim |
| pubmed-article:19364742 | lifeskim:mentions | umls-concept:C0557061 | lld:lifeskim |
| pubmed-article:19364742 | lifeskim:mentions | umls-concept:C1552617 | lld:lifeskim |
| pubmed-article:19364742 | lifeskim:mentions | umls-concept:C0282443 | lld:lifeskim |
| pubmed-article:19364742 | lifeskim:mentions | umls-concept:C0182400 | lld:lifeskim |
| pubmed-article:19364742 | pubmed:issue | 1668 | lld:pubmed |
| pubmed-article:19364742 | pubmed:dateCreated | 2009-6-29 | lld:pubmed |
| pubmed-article:19364742 | pubmed:abstractText | Following the ideas introduced by Huxley (Huxley 1957, Prog. Biophys. Biophys. Chem. 7, 255-318), it is generally supposed that muscle contraction is produced by temporary links, called crossbridges, between myosin and actin filaments, which form and break in a cyclic process driven by ATP splitting. Here we consider the interaction of the energy in the crossbridge, in its various states, and the force exerted. We discuss experiments in which the mechanical state of the crossbridge is changed by imposed movement and the energetic consequence observed as heat output and the converse experiments in which the energy content is changed by altering temperature and the mechanical consequences are observed. The thermodynamic relationship between the experiments is explained and, at the first sight, the relationship between the results of these two types of experiment appears paradoxical. However, we describe here how both of them can be explained by a model in which mechanical and energetic changes in the crossbridges occur in separate steps in a branching cycle. | lld:pubmed |
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| pubmed-article:19364742 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19364742 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19364742 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19364742 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19364742 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:19364742 | pubmed:issn | 0962-8452 | lld:pubmed |
| pubmed-article:19364742 | pubmed:author | pubmed-author:WoledgeR CRC | lld:pubmed |
| pubmed-article:19364742 | pubmed:author | pubmed-author:CurtinN ANA | lld:pubmed |
| pubmed-article:19364742 | pubmed:author | pubmed-author:BarclayC JCJ | lld:pubmed |
| pubmed-article:19364742 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:19364742 | pubmed:day | 7 | lld:pubmed |
| pubmed-article:19364742 | pubmed:volume | 276 | lld:pubmed |
| pubmed-article:19364742 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19364742 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19364742 | pubmed:pagination | 2685-95 | lld:pubmed |
| pubmed-article:19364742 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:19364742 | pubmed:meshHeading | pubmed-meshheading:19364742... | lld:pubmed |
| pubmed-article:19364742 | pubmed:meshHeading | pubmed-meshheading:19364742... | lld:pubmed |
| pubmed-article:19364742 | pubmed:meshHeading | pubmed-meshheading:19364742... | lld:pubmed |
| pubmed-article:19364742 | pubmed:meshHeading | pubmed-meshheading:19364742... | lld:pubmed |
| pubmed-article:19364742 | pubmed:meshHeading | pubmed-meshheading:19364742... | lld:pubmed |
| pubmed-article:19364742 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19364742 | pubmed:articleTitle | Temperature change as a probe of muscle crossbridge kinetics: a review and discussion. | lld:pubmed |
| pubmed-article:19364742 | pubmed:affiliation | Molecular Medicine Section, National Heart and Lung Institute, Imperial College London, , London SW7 2AZ, UK. r.woledge@imperial.ac.uk | lld:pubmed |
| pubmed-article:19364742 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19364742 | pubmed:publicationType | Review | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19364742 | lld:pubmed |
