| pubmed-article:19362831 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19362831 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:19362831 | lifeskim:mentions | umls-concept:C1880355 | lld:lifeskim |
| pubmed-article:19362831 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:19362831 | lifeskim:mentions | umls-concept:C0243072 | lld:lifeskim |
| pubmed-article:19362831 | pubmed:issue | 10 | lld:pubmed |
| pubmed-article:19362831 | pubmed:dateCreated | 2009-5-4 | lld:pubmed |
| pubmed-article:19362831 | pubmed:abstractText | A novel class of 3,6-disubstituted 2-pyridinecarboxamide derivatives was designed based on X-ray analysis of the 2-aminobenzamide lead class. Subsequent chemical modification led to the discovery of potent GK activators which eliminate potential toxicity concerns associated with an aniline group of the lead structure. Compound 7 demonstrated glucose lowering effect in a rat OGTT model. | lld:pubmed |
| pubmed-article:19362831 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19362831 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19362831 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19362831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19362831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19362831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19362831 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19362831 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19362831 | pubmed:month | May | lld:pubmed |
| pubmed-article:19362831 | pubmed:issn | 1464-3405 | lld:pubmed |
| pubmed-article:19362831 | pubmed:author | pubmed-author:SasakiKaoriK | lld:pubmed |
| pubmed-article:19362831 | pubmed:author | pubmed-author:WatanabeHitom... | lld:pubmed |
| pubmed-article:19362831 | pubmed:author | pubmed-author:SasakiYasuhir... | lld:pubmed |
| pubmed-article:19362831 | pubmed:author | pubmed-author:KamataKenjiK | lld:pubmed |
| pubmed-article:19362831 | pubmed:author | pubmed-author:MitsuyaMorihi... | lld:pubmed |
| pubmed-article:19362831 | pubmed:author | pubmed-author:NishimuraTeru... | lld:pubmed |
| pubmed-article:19362831 | pubmed:author | pubmed-author:NagataYasufum... | lld:pubmed |
| pubmed-article:19362831 | pubmed:author | pubmed-author:HosakaHidekaH | lld:pubmed |
| pubmed-article:19362831 | pubmed:author | pubmed-author:OhyamaSumikaS | lld:pubmed |
| pubmed-article:19362831 | pubmed:author | pubmed-author:EikiJun-ichiJ | lld:pubmed |
| pubmed-article:19362831 | pubmed:author | pubmed-author:BambaMakotoM | lld:pubmed |
| pubmed-article:19362831 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19362831 | pubmed:day | 15 | lld:pubmed |
| pubmed-article:19362831 | pubmed:volume | 19 | lld:pubmed |
| pubmed-article:19362831 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19362831 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19362831 | pubmed:pagination | 2718-21 | lld:pubmed |
| pubmed-article:19362831 | pubmed:meshHeading | pubmed-meshheading:19362831... | lld:pubmed |
| pubmed-article:19362831 | pubmed:meshHeading | pubmed-meshheading:19362831... | lld:pubmed |
| pubmed-article:19362831 | pubmed:meshHeading | pubmed-meshheading:19362831... | lld:pubmed |
| pubmed-article:19362831 | pubmed:meshHeading | pubmed-meshheading:19362831... | lld:pubmed |
| pubmed-article:19362831 | pubmed:meshHeading | pubmed-meshheading:19362831... | lld:pubmed |
| pubmed-article:19362831 | pubmed:meshHeading | pubmed-meshheading:19362831... | lld:pubmed |
| pubmed-article:19362831 | pubmed:meshHeading | pubmed-meshheading:19362831... | lld:pubmed |
| pubmed-article:19362831 | pubmed:meshHeading | pubmed-meshheading:19362831... | lld:pubmed |
| pubmed-article:19362831 | pubmed:meshHeading | pubmed-meshheading:19362831... | lld:pubmed |
| pubmed-article:19362831 | pubmed:meshHeading | pubmed-meshheading:19362831... | lld:pubmed |
| pubmed-article:19362831 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19362831 | pubmed:articleTitle | Discovery of novel 3,6-disubstituted 2-pyridinecarboxamide derivatives as GK activators. | lld:pubmed |
| pubmed-article:19362831 | pubmed:affiliation | Banyu Tsukuba Research Institute, Banyu Pharmaceutical Co. Ltd, Okubo, Tsukuba, Ibaraki, Japan. morihiro_mitsuya@merck.com | lld:pubmed |
| pubmed-article:19362831 | pubmed:publicationType | Journal Article | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:19362831 | lld:chembl |
