| pubmed-article:1935653 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1935653 | lifeskim:mentions | umls-concept:C0020479 | lld:lifeskim |
| pubmed-article:1935653 | lifeskim:mentions | umls-concept:C0020861 | lld:lifeskim |
| pubmed-article:1935653 | lifeskim:mentions | umls-concept:C0178650 | lld:lifeskim |
| pubmed-article:1935653 | pubmed:issue | 45 | lld:pubmed |
| pubmed-article:1935653 | pubmed:dateCreated | 1991-12-16 | lld:pubmed |
| pubmed-article:1935653 | pubmed:abstractText | A 42-year-old woman, found to have increased blood-lipid levels, developed hand-line xanthomas 3 months later. She also had an increased erythrocyte-sedimentation rate and a type lambda monoclonal IgM abnormality. In the course of the following 4 years the IgM concentration rose (from 5.8 to 12.3 g/l) steadily and synchronously with those of the triglycerides (from 147 to 391 mg/dl) and cholesterol (from 212 to 380 mg/dl). During the entire period of observation the ratio of VLDL cholesterol and triglyceride concentrations was elevated (greater than 0.4; normal: less than 0.3). Division of the lipoprotein fractions pointed to a type III hyperlipoproteinaemia. She also had an abnormality of lipid metabolism on the basis of a genetic defect (apolipoprotein-E2 homozygotism), which only manifested itself when an additional factor, IgM paraproteinaemia, was present. Paraproteins thus apparently interfered with the breakdown of the lipoproteins. Neither bezafibrate in increasing doses (200-800 mg daily) with low-fat diet nor administration of lovastatin (20 mg twice daily) together with nicotinic acid (500 mg twice daily) were adequate treatment for this form of auto-immune hyperlipidaemia. | lld:pubmed |
| pubmed-article:1935653 | pubmed:language | ger | lld:pubmed |
| pubmed-article:1935653 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1935653 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:1935653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1935653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1935653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1935653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1935653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1935653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1935653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1935653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1935653 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1935653 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1935653 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:1935653 | pubmed:issn | 0012-0472 | lld:pubmed |
| pubmed-article:1935653 | pubmed:author | pubmed-author:KüblerWW | lld:pubmed |
| pubmed-article:1935653 | pubmed:author | pubmed-author:SchulerGG | lld:pubmed |
| pubmed-article:1935653 | pubmed:author | pubmed-author:von... | lld:pubmed |
| pubmed-article:1935653 | pubmed:author | pubmed-author:HambrechtRR | lld:pubmed |
| pubmed-article:1935653 | pubmed:author | pubmed-author:TischbirekKK | lld:pubmed |
| pubmed-article:1935653 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1935653 | pubmed:day | 8 | lld:pubmed |
| pubmed-article:1935653 | pubmed:volume | 116 | lld:pubmed |
| pubmed-article:1935653 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1935653 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1935653 | pubmed:pagination | 1710-4 | lld:pubmed |
| pubmed-article:1935653 | pubmed:dateRevised | 2006-11-15 | lld:pubmed |
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| pubmed-article:1935653 | pubmed:meshHeading | pubmed-meshheading:1935653-... | lld:pubmed |
| pubmed-article:1935653 | pubmed:meshHeading | pubmed-meshheading:1935653-... | lld:pubmed |
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| pubmed-article:1935653 | pubmed:meshHeading | pubmed-meshheading:1935653-... | lld:pubmed |
| pubmed-article:1935653 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1935653 | pubmed:articleTitle | [Type III hyperlipoproteinemia in monoclonal IgM gammopathy]. | lld:pubmed |
| pubmed-article:1935653 | pubmed:affiliation | Abteilung Innere Medizin III, Universität Heidelberg. | lld:pubmed |
| pubmed-article:1935653 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:1935653 | pubmed:publicationType | English Abstract | lld:pubmed |
| pubmed-article:1935653 | pubmed:publicationType | Case Reports | lld:pubmed |
