| pubmed-article:1929336 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1929336 | lifeskim:mentions | umls-concept:C0038404 | lld:lifeskim |
| pubmed-article:1929336 | lifeskim:mentions | umls-concept:C0004610 | lld:lifeskim |
| pubmed-article:1929336 | lifeskim:mentions | umls-concept:C1314792 | lld:lifeskim |
| pubmed-article:1929336 | lifeskim:mentions | umls-concept:C0312853 | lld:lifeskim |
| pubmed-article:1929336 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:1929336 | pubmed:dateCreated | 1991-11-1 | lld:pubmed |
| pubmed-article:1929336 | pubmed:abstractText | Between 1 January 1984 and 31 December 1987, 206 enterococcal blood isolates at the University of Wisconsin Hospital and Clinics were analyzed for high-level aminoglycoside resistance (hereafter high-level aminoglycoside resistance is simply referred to as "resistance") and hemolysin production. Of 190 Enterococcus faecalis isolates, 68 (35.8%) were resistant to gentamicin. Of these 68 strains, 67 (98.5%) contained a gene coding for the bifunctional aminoglycoside-modifying 6'-aminoglycoside acetyltransferase-2"-aminoglycoside phosphotransferase [AAC(6')-APH(2")] enzyme. Of 190 isolates, 85 (44.7%) were hemolytic and contained a gene coding for component A of the enterococcal hemolysin. Sixty-two of 68 (91.2%) gentamicin-resistant isolates but only 23 of 122 (18.8%) gentamicin-susceptible isolates were hemolytic (P less than 0.001). Twelve of the hemolytic, gentamicin-resistant E. faecalis blood isolates, but only 2 of 9 nonhemolytic or gentamicin-susceptible isolates, had identical chromosomal DNA restriction endonuclease digestion patterns, suggesting a common derivation for these strains. A historical cohort study from 1 July 1985 to 31 March 1987 identified by regression analysis postsurgical intensive care unit status (odds ratio [OR], 5.0; 95% confidence interval [CI], 1.1 to 22.8) and prior treatment with an expanded- or broad-spectrum cephalosporin (OR, 3.0; 95% CI, 0.9 to 10.1) as risk factors for gentamicin-resistant E. faecalis bacteremia. Patients with hemolytic, gentamicin-resistant E. faecalis bacteremia had a fivefold-increased risk for death within 3 weeks of their bacteremia compared with patients with nonhemolytic, gentamicin-susceptible strains (95% CI, 1.0 to 25.4). | lld:pubmed |
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| pubmed-article:1929336 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1929336 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1929336 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1929336 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1929336 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:1929336 | pubmed:issn | 0066-4804 | lld:pubmed |
| pubmed-article:1929336 | pubmed:author | pubmed-author:HuyckeM MMM | lld:pubmed |
| pubmed-article:1929336 | pubmed:author | pubmed-author:SpiegelC ACA | lld:pubmed |
| pubmed-article:1929336 | pubmed:author | pubmed-author:GilmoreM SMS | lld:pubmed |
| pubmed-article:1929336 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1929336 | pubmed:volume | 35 | lld:pubmed |
| pubmed-article:1929336 | pubmed:geneSymbol | AAC(6')-APH(2'') | lld:pubmed |
| pubmed-article:1929336 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1929336 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1929336 | pubmed:pagination | 1626-34 | lld:pubmed |
| pubmed-article:1929336 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:1929336 | pubmed:meshHeading | pubmed-meshheading:1929336-... | lld:pubmed |
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| pubmed-article:1929336 | pubmed:meshHeading | pubmed-meshheading:1929336-... | lld:pubmed |
| pubmed-article:1929336 | pubmed:meshHeading | pubmed-meshheading:1929336-... | lld:pubmed |
| pubmed-article:1929336 | pubmed:meshHeading | pubmed-meshheading:1929336-... | lld:pubmed |
| pubmed-article:1929336 | pubmed:meshHeading | pubmed-meshheading:1929336-... | lld:pubmed |
| pubmed-article:1929336 | pubmed:meshHeading | pubmed-meshheading:1929336-... | lld:pubmed |
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| pubmed-article:1929336 | pubmed:meshHeading | pubmed-meshheading:1929336-... | lld:pubmed |
| pubmed-article:1929336 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1929336 | pubmed:articleTitle | Bacteremia caused by hemolytic, high-level gentamicin-resistant Enterococcus faecalis. | lld:pubmed |
