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pubmed-article:19285711pubmed:abstractTextTo investigate whether survivin-specific cytotoxic T lymphocytes (CTLs) could be induced by dendritic cells (DCs) transduced with survivin gene by adenoviral vector, and whether these CTLs would display cytotoxic activities against human urologic cancer cell lines. Survivin, a member of the inhibitor of apoptosis protein family, is expressed in most malignancies, but not in normal tissue.lld:pubmed
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pubmed-article:19285711pubmed:articleTitleDendritic cells with transduced survivin gene induce specific cytotoxic T lymphocytes in human urologic cancer cell lines.lld:pubmed
pubmed-article:19285711pubmed:affiliationDepartment of Urology, Wakayama Medical University, Wakayama, Japan. kzro@wakayamamed.ac.jplld:pubmed
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