| pubmed-article:19284572 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19284572 | lifeskim:mentions | umls-concept:C1882071 | lld:lifeskim |
| pubmed-article:19284572 | lifeskim:mentions | umls-concept:C0017337 | lld:lifeskim |
| pubmed-article:19284572 | lifeskim:mentions | umls-concept:C0872079 | lld:lifeskim |
| pubmed-article:19284572 | lifeskim:mentions | umls-concept:C1514468 | lld:lifeskim |
| pubmed-article:19284572 | lifeskim:mentions | umls-concept:C0220885 | lld:lifeskim |
| pubmed-article:19284572 | lifeskim:mentions | umls-concept:C0871161 | lld:lifeskim |
| pubmed-article:19284572 | pubmed:dateCreated | 2009-4-1 | lld:pubmed |
| pubmed-article:19284572 | pubmed:abstractText | Human cells of various tissue types differ greatly in morphology despite having the same set of genetic information. Some genes are expressed in all cell types to perform house-keeping functions, while some are selectively expressed to perform tissue-specific functions. In this study, we wished to elucidate how proteins encoded by human house-keeping genes and tissue-specific genes are organized in human protein-protein interaction networks. We constructed protein-protein interaction networks for different tissue types using two gene expression datasets and one protein-protein interaction database. We then calculated three network indices of topological importance, the degree, closeness, and betweenness centralities, to measure the network position of proteins encoded by house-keeping and tissue-specific genes, and quantified their local connectivity structure. | lld:pubmed |
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| pubmed-article:19284572 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19284572 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19284572 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19284572 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19284572 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19284572 | pubmed:issn | 1752-0509 | lld:pubmed |
| pubmed-article:19284572 | pubmed:author | pubmed-author:HwangMing-Jin... | lld:pubmed |
| pubmed-article:19284572 | pubmed:author | pubmed-author:LinWen-HsienW... | lld:pubmed |
| pubmed-article:19284572 | pubmed:author | pubmed-author:LiuWei-ChungW... | lld:pubmed |
| pubmed-article:19284572 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19284572 | pubmed:volume | 3 | lld:pubmed |
| pubmed-article:19284572 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19284572 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19284572 | pubmed:pagination | 32 | lld:pubmed |
| pubmed-article:19284572 | pubmed:dateRevised | 2010-9-23 | lld:pubmed |
| pubmed-article:19284572 | pubmed:meshHeading | pubmed-meshheading:19284572... | lld:pubmed |
| pubmed-article:19284572 | pubmed:meshHeading | pubmed-meshheading:19284572... | lld:pubmed |
| pubmed-article:19284572 | pubmed:meshHeading | pubmed-meshheading:19284572... | lld:pubmed |
| pubmed-article:19284572 | pubmed:meshHeading | pubmed-meshheading:19284572... | lld:pubmed |
| pubmed-article:19284572 | pubmed:meshHeading | pubmed-meshheading:19284572... | lld:pubmed |
| pubmed-article:19284572 | pubmed:meshHeading | pubmed-meshheading:19284572... | lld:pubmed |
| pubmed-article:19284572 | pubmed:meshHeading | pubmed-meshheading:19284572... | lld:pubmed |
| pubmed-article:19284572 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19284572 | pubmed:articleTitle | Topological and organizational properties of the products of house-keeping and tissue-specific genes in protein-protein interaction networks. | lld:pubmed |
| pubmed-article:19284572 | pubmed:affiliation | Institute of Biomedical Informatics, National Yang-Ming University, Taipei, Taiwan. heliosy@gmail.com | lld:pubmed |
| pubmed-article:19284572 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19284572 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
