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pubmed-article:19276257pubmed:abstractTextHuman interleukin-21 (IL-21) is a class I cytokine that mediates activation of CD8(+) T cells, natural killer (NK) cells, and other cell types. We report final clinical and biological results of a phase II study of recombinant human IL-21 (rIL-21) in patients with metastatic melanoma.lld:pubmed
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pubmed-article:19276257pubmed:articleTitleClinical and biological efficacy of recombinant human interleukin-21 in patients with stage IV malignant melanoma without prior treatment: a phase IIa trial.lld:pubmed
pubmed-article:19276257pubmed:affiliationLudwig Oncology Unit, Austin Health, Melbourne, Victoria, Australia.lld:pubmed
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