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pubmed-article:19269629pubmed:abstractTextA series of beta-arabino glycosyl sulfones with varying alkyl chain lengths were synthesised in a stereoselective fashion as putative mimics of decaprenolphosphoarabinose (DPA), and as potential inhibitors of mycobacterial cell wall biosynthesis. Biological testing against Mycobacterium bovis BCG revealed low to moderate anti-mycobacterial activity with marked dependence on alkyl chain length, which was maximal for a C-12 chain.lld:pubmed
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pubmed-article:19269629pubmed:articleTitleStereoselective synthesis of beta-arabino glycosyl sulfones as potential inhibitors of mycobacterial cell wall biosynthesis.lld:pubmed
pubmed-article:19269629pubmed:affiliationDepartment of Chemistry, Chemistry Research Laboratory, University of Oxford, Oxford, UK.lld:pubmed
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