(V600E)BRAF is associated with disabled feedback inhibition of RAF-MEK signaling and elevated transcriptional output of the pathway.

Source:http://linkedlifedata.com/resource/pubmed/id/19251651

Proc. Natl. Acad. Sci. U.S.A. 2009 Mar 17 106 11 4519-24

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PMID
19251651