| pubmed-article:19243081 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19243081 | lifeskim:mentions | umls-concept:C0043393 | lld:lifeskim |
| pubmed-article:19243081 | lifeskim:mentions | umls-concept:C0319549 | lld:lifeskim |
| pubmed-article:19243081 | lifeskim:mentions | umls-concept:C1513400 | lld:lifeskim |
| pubmed-article:19243081 | lifeskim:mentions | umls-concept:C0600597 | lld:lifeskim |
| pubmed-article:19243081 | lifeskim:mentions | umls-concept:C1335144 | lld:lifeskim |
| pubmed-article:19243081 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:19243081 | pubmed:dateCreated | 2009-3-5 | lld:pubmed |
| pubmed-article:19243081 | pubmed:abstractText | The bottom fermenting yeast Saccharomyces pastorianus is reported to have arisen as a natural hybrid of two yeast strains, S. cerevisiae and S. bayanus. The S. pastorianus genome includes S. cerevisiae-type (Sc-type) genes and orthologous lager-fermenting-yeast specific-type (Lg-type) genes derived from S. cerevisiae and S. bayanus, respectively. To gain insights into the physiological properties of S. pastorianus, we developed an in situ synthesized 60-mer oligonucleotide microarray for gene expression monitoring of these orthologous genes, consisting of approximately 6600 Sc-type genes and 3200 Lg-type genes. A comparison of the transcriptional profile of orthologous genes (e.g. Sc-type and Lg-type genes) in S. cerevisiae or S. bayanus demonstrated the feasibility of performing gene expression studies with this microarray. Genome-wide analysis of S. pastorianus with this microarray could clearly distinguish more than 67% of the expressed orthologous genes. Furthermore, it was shown that the gene expression of particular Lg-type genes differed from that of the orthologous Sc-type genes, suggesting that some Lg-type and Sc-type genes may have different functional roles. We conclude that the oligonucleotide microarray that we constructed is a powerful tool for the monitoring of gene expression of the orthologous genes of S. pastorianus. | lld:pubmed |
| pubmed-article:19243081 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19243081 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243081 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19243081 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243081 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243081 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243081 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19243081 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19243081 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:19243081 | pubmed:issn | 1097-0061 | lld:pubmed |
| pubmed-article:19243081 | pubmed:author | pubmed-author:KobayashiOsam... | lld:pubmed |
| pubmed-article:19243081 | pubmed:author | pubmed-author:YoshidaSatosh... | lld:pubmed |
| pubmed-article:19243081 | pubmed:author | pubmed-author:YoshimotoHiro... | lld:pubmed |
| pubmed-article:19243081 | pubmed:author | pubmed-author:MinatoToshiko... | lld:pubmed |
| pubmed-article:19243081 | pubmed:author | pubmed-author:MizutaniSator... | lld:pubmed |
| pubmed-article:19243081 | pubmed:author | pubmed-author:ShimadaEmikoE | lld:pubmed |
| pubmed-article:19243081 | pubmed:author | pubmed-author:IshiguroTatsu... | lld:pubmed |
| pubmed-article:19243081 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19243081 | pubmed:volume | 26 | lld:pubmed |
| pubmed-article:19243081 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19243081 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19243081 | pubmed:pagination | 147-65 | lld:pubmed |
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| pubmed-article:19243081 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19243081 | pubmed:articleTitle | Expression profiling of the bottom fermenting yeast Saccharomyces pastorianus orthologous genes using oligonucleotide microarrays. | lld:pubmed |
| pubmed-article:19243081 | pubmed:affiliation | Central Laboratories for Frontier Technology, Kirin Holdings Co Ltd, Yokohama-shi, Kanagawa, Japan. | lld:pubmed |
| pubmed-article:19243081 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19243081 | pubmed:publicationType | Evaluation Studies | lld:pubmed |
