| pubmed-article:19223894 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19223894 | lifeskim:mentions | umls-concept:C0001175 | lld:lifeskim |
| pubmed-article:19223894 | lifeskim:mentions | umls-concept:C0681698 | lld:lifeskim |
| pubmed-article:19223894 | lifeskim:mentions | umls-concept:C0596244 | lld:lifeskim |
| pubmed-article:19223894 | lifeskim:mentions | umls-concept:C1414461 | lld:lifeskim |
| pubmed-article:19223894 | lifeskim:mentions | umls-concept:C0887947 | lld:lifeskim |
| pubmed-article:19223894 | lifeskim:mentions | umls-concept:C0022277 | lld:lifeskim |
| pubmed-article:19223894 | lifeskim:mentions | umls-concept:C0449774 | lld:lifeskim |
| pubmed-article:19223894 | lifeskim:mentions | umls-concept:C1547564 | lld:lifeskim |
| pubmed-article:19223894 | lifeskim:mentions | umls-concept:C0449435 | lld:lifeskim |
| pubmed-article:19223894 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:19223894 | pubmed:dateCreated | 2009-3-4 | lld:pubmed |
| pubmed-article:19223894 | pubmed:abstractText | A record-linkage study was carried out between the Italian AIDS Registry and 24 Italian cancer registries to compare cancer excess among persons with HIV/AIDS (PWHA) before and after the introduction of highly active antiretroviral therapy (HAART) in 1996. Standardised incidence ratios (SIR) were computed in 21951 AIDS cases aged 16-69 years reported between 1986 and 2005. Of 101 669 person-years available, 45 026 were after 1996. SIR for Kaposi sarcoma (KS) and non-Hodgkin lymphoma greatly decreased in 1997-2004 compared with 1986-1996, but high SIRs for KS persisted in the increasingly large fraction of PWHA who had an interval of <1 year between first HIV-positive test and AIDS diagnosis. A significant excess of liver cancer (SIR=6.4) emerged in 1997-2004, whereas the SIRs for cancer of the cervix (41.5), anus (44.0), lung (4.1), brain (3.2), skin (non-melanoma, 1.8), Hodgkin lymphoma (20.7), myeloma (3.9), and non-AIDS-defining cancers (2.2) were similarly elevated in the two periods. The excess of some potentially preventable cancers in PWHA suggests that HAART use must be accompanied by cancer-prevention strategies, notably antismoking and cervical cancer screening programmes. Improvements in the timely identification of HIV-positive individuals are also a priority in Italy to avoid the adverse consequences of delayed HAART use. | lld:pubmed |
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| pubmed-article:19223894 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19223894 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19223894 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19223894 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19223894 | pubmed:month | Mar | lld:pubmed |
| pubmed-article:19223894 | pubmed:issn | 1532-1827 | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:RussoAA | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:FuscoMM | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:FedericoMM | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:VercelliMM | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:FalciniFF | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:LiseMM | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:FranceschiSS | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:ZambonPP | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:BudroniMM | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:DonathJJ | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:ZanettiRR | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:TagliabueGG | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:TuminoRR | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:SerrainoDD | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:SuligoiBB | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:FerrettiSS | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:PiselliPP | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:De LisiVV | lld:pubmed |
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| pubmed-article:19223894 | pubmed:author | pubmed-author:LiminaR MRM | lld:pubmed |
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| pubmed-article:19223894 | pubmed:author | pubmed-author:IntrieriTT | lld:pubmed |
| pubmed-article:19223894 | pubmed:author | pubmed-author:Cancer and... | lld:pubmed |
| pubmed-article:19223894 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19223894 | pubmed:day | 10 | lld:pubmed |
| pubmed-article:19223894 | pubmed:volume | 100 | lld:pubmed |
| pubmed-article:19223894 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19223894 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19223894 | pubmed:pagination | 840-7 | lld:pubmed |
| pubmed-article:19223894 | pubmed:dateRevised | 2010-9-22 | lld:pubmed |
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