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pubmed-article:19198651pubmed:abstractTextThe relationship of elevated T cell activation to altered T cell differentiation profiles, each defining features of HIV-1 infection, has not been extensively explored. We hypothesized that anti-retroviral suppression of T cell activation levels would lead to alterations in the T cell differentiation of total and HIV-1 specific CD8+ T cell responses among recently HIV-1 infected adults.lld:pubmed
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pubmed-article:19198651pubmed:articleTitleHigh CD8+ T cell activation marks a less differentiated HIV-1 specific CD8+ T cell response that is not altered by suppression of viral replication.lld:pubmed
pubmed-article:19198651pubmed:affiliationDepartment of Medicine, HIV/AIDS Division, San Francisco General Hospital, University of California San Francisco, San Francisco, California, United States of America. jbarbour@php.ucsf.edulld:pubmed
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