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pubmed-article:19175347pubmed:abstractTextA bisamidinium catalyst has been designed for the Claisen rearrangement. The primary design feature is a dual hydrogen bonding array that can coordinate a singular oxygen atom of the substrate. The ability to function as a dual hydrogen donor is key as the bisamidinium accelerates the Claisen rearrangement to a greater extent than Brønsted acids with lower pK(a) values.lld:pubmed
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pubmed-article:19175347pubmed:dateRevised2010-9-22lld:pubmed
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pubmed-article:19175347pubmed:articleTitleDesign of a bisamidinium claisen rearrangement catalyst for monodentate substrates.lld:pubmed
pubmed-article:19175347pubmed:affiliationDepartment of Chemistry, Roy and Diana Vagelos Laboratories, University of Pennsylvania, Philadelphia, Pennsylvania 19104, USA.lld:pubmed
pubmed-article:19175347pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19175347pubmed:publicationTypeResearch Support, U.S. Gov't, Non-P.H.S.lld:pubmed
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