| pubmed-article:1915298 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:1915298 | lifeskim:mentions | umls-concept:C0043393 | lld:lifeskim |
| pubmed-article:1915298 | lifeskim:mentions | umls-concept:C0017725 | lld:lifeskim |
| pubmed-article:1915298 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:1915298 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:1915298 | lifeskim:mentions | umls-concept:C1336789 | lld:lifeskim |
| pubmed-article:1915298 | lifeskim:mentions | umls-concept:C0040649 | lld:lifeskim |
| pubmed-article:1915298 | lifeskim:mentions | umls-concept:C1414945 | lld:lifeskim |
| pubmed-article:1915298 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:1915298 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:1915298 | lifeskim:mentions | umls-concept:C2587213 | lld:lifeskim |
| pubmed-article:1915298 | lifeskim:mentions | umls-concept:C1707310 | lld:lifeskim |
| pubmed-article:1915298 | pubmed:issue | 11 | lld:pubmed |
| pubmed-article:1915298 | pubmed:dateCreated | 1991-11-18 | lld:pubmed |
| pubmed-article:1915298 | pubmed:abstractText | Glucose repression is a global regulatory mechanism in yeast. We have investigated how glucose regulates the GAL genes, which are required for galactose fermentation. We found that the GAL genes are controlled by a transcriptional cascade. Thus, GAL4, which encodes an activator of the GAL genes, is repressed by MIG1, a zinc finger protein that binds to the GAL4 promoter. MIG1 has a dual role in control of the GAL genes, since MIG1 also binds to the promoter of GAL1, a gene regulated by GAL4. A disruption of MIG1 interacts synergistically with a disruption of GAL80, a gene involved in galactose induction. This suggests that the MIG1-dependent response to glucose is amplified by down-regulation of the induction pathway. | lld:pubmed |
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| pubmed-article:1915298 | pubmed:language | eng | lld:pubmed |
| pubmed-article:1915298 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:1915298 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:1915298 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:1915298 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:1915298 | pubmed:issn | 0261-4189 | lld:pubmed |
| pubmed-article:1915298 | pubmed:author | pubmed-author:RonneHH | lld:pubmed |
| pubmed-article:1915298 | pubmed:author | pubmed-author:CarlbergMM | lld:pubmed |
| pubmed-article:1915298 | pubmed:author | pubmed-author:NehlinJ OJO | lld:pubmed |
| pubmed-article:1915298 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:1915298 | pubmed:volume | 10 | lld:pubmed |
| pubmed-article:1915298 | pubmed:geneSymbol | GAL | lld:pubmed |
| pubmed-article:1915298 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:1915298 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:1915298 | pubmed:pagination | 3373-7 | lld:pubmed |
| pubmed-article:1915298 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:1915298 | pubmed:year | 1991 | lld:pubmed |
| pubmed-article:1915298 | pubmed:articleTitle | Control of yeast GAL genes by MIG1 repressor: a transcriptional cascade in the glucose response. | lld:pubmed |
| pubmed-article:1915298 | pubmed:affiliation | Ludwig Institute for Cancer Research, Biomedical Center, Uppsala, Sweden. | lld:pubmed |
| pubmed-article:1915298 | pubmed:publicationType | Journal Article | lld:pubmed |
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