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pubmed-article:19139291pubmed:abstractTextExperience with anidulafungin against Candida krusei is limited. Immunosuppressed mice were injected with 1.3 x 10(7) to 1.5 x 10(7) CFU of C. krusei. Animals were treated with saline, 40 mg/kg fluconazole, 1 mg/kg amphotericin B, or 10 and 20 mg/kg anidulafungin for 5 days. Anidulafungin improved survival and significantly reduced the number of CFU/g in kidneys and serum beta-glucan levels.lld:pubmed
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pubmed-article:19139291pubmed:articleTitleActivity of anidulafungin in a murine model of Candida krusei infection: evaluation of mortality and disease burden by quantitative tissue cultures and measurement of serum (1,3)-beta-D-glucan levels.lld:pubmed
pubmed-article:19139291pubmed:affiliationDivision of Infectious Diseases, University of Texas Medical School at Houston, Houston, Texas 77030, USA. Luis.Ostrosky-Zeichner@uth.tmc.edulld:pubmed
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