| pubmed-article:19125195 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19125195 | lifeskim:mentions | umls-concept:C0332307 | lld:lifeskim |
| pubmed-article:19125195 | lifeskim:mentions | umls-concept:C0011860 | lld:lifeskim |
| pubmed-article:19125195 | lifeskim:mentions | umls-concept:C0011884 | lld:lifeskim |
| pubmed-article:19125195 | lifeskim:mentions | umls-concept:C1335238 | lld:lifeskim |
| pubmed-article:19125195 | lifeskim:mentions | umls-concept:C0332281 | lld:lifeskim |
| pubmed-article:19125195 | lifeskim:mentions | umls-concept:C0034987 | lld:lifeskim |
| pubmed-article:19125195 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:19125195 | lifeskim:mentions | umls-concept:C0679622 | lld:lifeskim |
| pubmed-article:19125195 | lifeskim:mentions | umls-concept:C0022277 | lld:lifeskim |
| pubmed-article:19125195 | lifeskim:mentions | umls-concept:C1880022 | lld:lifeskim |
| pubmed-article:19125195 | lifeskim:mentions | umls-concept:C0205314 | lld:lifeskim |
| pubmed-article:19125195 | pubmed:dateCreated | 2009-1-6 | lld:pubmed |
| pubmed-article:19125195 | pubmed:abstractText | Peroxisome proliferator-activated receptor gamma polymorphisms have been widely associated with type 2 diabetes, although their role in the pathogenesis of vascular complications is not yet demonstrated. In this study, a cohort of 211 type 2 diabetes, 205 obese, and 254 control individuals was genotyped for Pro12Ala, C1431T, C-2821T polymorphisms, and for a newly identified polymorphism (A-2819G). The above-mentioned polymorphisms were analyzed by gene-specific PCR and direct sequencing of all samples. A significant difference was found for -2819G frequency when patients with type 2 diabetes-particularly diabetic women with the proliferative retinopathy-were compared with healthy control individuals. In conclusion, we identified a novel polymorphism, A-2819G, in PPARG gene, and we found it to be associated with type 2 diabetes and proliferative retinopathy in diabetic females. In the analyzed population, this variant represents a genetic risk factor for developing the diabetic retinopathy, whereas Pro12Ala and C1431T do not. | lld:pubmed |
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| pubmed-article:19125195 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19125195 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19125195 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:19125195 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19125195 | pubmed:issn | 1110-7251 | lld:pubmed |
| pubmed-article:19125195 | pubmed:author | pubmed-author:GiuglianoDari... | lld:pubmed |
| pubmed-article:19125195 | pubmed:author | pubmed-author:EspositoKathe... | lld:pubmed |
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| pubmed-article:19125195 | pubmed:author | pubmed-author:CiotolaMiryam... | lld:pubmed |
| pubmed-article:19125195 | pubmed:author | pubmed-author:CasamassimiAm... | lld:pubmed |
| pubmed-article:19125195 | pubmed:author | pubmed-author:SchisanoBruno... | lld:pubmed |
| pubmed-article:19125195 | pubmed:author | pubmed-author:CostaValerioV | lld:pubmed |
| pubmed-article:19125195 | pubmed:author | pubmed-author:CaponeMariael... | lld:pubmed |
| pubmed-article:19125195 | pubmed:author | pubmed-author:VillaniAngela... | lld:pubmed |
| pubmed-article:19125195 | pubmed:author | pubmed-author:IannellaRosaR | lld:pubmed |
| pubmed-article:19125195 | pubmed:author | pubmed-author:CorradoFelici... | lld:pubmed |
| pubmed-article:19125195 | pubmed:author | pubmed-author:SantangeloFra... | lld:pubmed |
| pubmed-article:19125195 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19125195 | pubmed:volume | 2009 | lld:pubmed |
| pubmed-article:19125195 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19125195 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19125195 | pubmed:pagination | 126917 | lld:pubmed |
| pubmed-article:19125195 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
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| pubmed-article:19125195 | pubmed:meshHeading | pubmed-meshheading:19125195... | lld:pubmed |
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| pubmed-article:19125195 | pubmed:meshHeading | pubmed-meshheading:19125195... | lld:pubmed |
| pubmed-article:19125195 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19125195 | pubmed:articleTitle | Characterization of a novel polymorphism in PPARG regulatory region associated with type 2 diabetes and diabetic retinopathy in Italy. | lld:pubmed |
| pubmed-article:19125195 | pubmed:affiliation | Institute of Genetics and Biophysics A. Buzzati-Traverso (IGB), National Research Council (CNR), Naples, Italy. | lld:pubmed |
| pubmed-article:19125195 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19125195 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:5468 | entrezgene:pubmed | pubmed-article:19125195 | lld:entrezgene |
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