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pubmed-article:19121783pubmed:dateCreated2009-1-5lld:pubmed
pubmed-article:19121783pubmed:abstractTextMetabolic syndrome (MS) can be linked to the progression of chronic renal transplant dysfunction (CRTD). Hyperfiltration in transplanted patients is a further risk factor for MS and for the progression of CRTD. Many studies show in kidney-transplanted subjects a prevalence of MS at 60% after 6 years posttransplantation. We studied 182 patients (126 men and 56 women) with functioning renal transplant in Messina and Rovigo Renal Units. In our patients we saw at 6 years postkidney transplant in men a prevalence of MS at 20% (NCEPATPIII criteria) or 30% (Rovigo-Messina more strict criteria), and women at 6 years posttransplantation a prevalence of MS at 25% (NCEPATPIII criteria) or 50% (Rovigo-Messina criteria). In our patients, the period of graft function was over 15 years. This result is due to continued follow-up of metabolic parameters and to moderate protein (0.8-0.9 g/kg/day), low lipid, and low caloric intake. These strategies permit the avoidance of hyperfiltration, the reduction of hyperlipidemia and obesity. Special attention is due to women 50-65 years old. In these patients the prevalence of metabolic syndrome 6 years posttransplant is very high (60%). Postmenopausal syndrome is an additional risk factor for MS, atherosclerosis, and the progression of CRTD.lld:pubmed
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pubmed-article:19121783pubmed:year2009lld:pubmed
pubmed-article:19121783pubmed:articleTitleMetabolic syndrome after kidney transplantation.lld:pubmed
pubmed-article:19121783pubmed:affiliationCattedra di Nefrologia, Università di Messina, SOC di Nefrologia-Nutrizione Clinica ULSS 18 Rovigo, Italy.lld:pubmed
pubmed-article:19121783pubmed:publicationTypeJournal Articlelld:pubmed