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pubmed-article:19108770pubmed:abstractTextCells often respond to external signals by altering their gene expression. The external signaling information is transduced and typically encoded in concentrations of relevant transcription factors. A recent study demonstrates that, by encoding this information in the frequency with which genes 'see' a transcription factor, the expression of hundreds of genes can be modulated in a linearly proportional manner.lld:pubmed
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pubmed-article:19108770pubmed:articleTitleGene expression: dialing up the frequency.lld:pubmed
pubmed-article:19108770pubmed:affiliationDepartment of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA. narendra@mit.edulld:pubmed
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