| pubmed-article:19067947 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19067947 | lifeskim:mentions | umls-concept:C0026339 | lld:lifeskim |
| pubmed-article:19067947 | lifeskim:mentions | umls-concept:C0034493 | lld:lifeskim |
| pubmed-article:19067947 | lifeskim:mentions | umls-concept:C0026336 | lld:lifeskim |
| pubmed-article:19067947 | lifeskim:mentions | umls-concept:C0031740 | lld:lifeskim |
| pubmed-article:19067947 | lifeskim:mentions | umls-concept:C0458827 | lld:lifeskim |
| pubmed-article:19067947 | lifeskim:mentions | umls-concept:C1261287 | lld:lifeskim |
| pubmed-article:19067947 | lifeskim:mentions | umls-concept:C0245194 | lld:lifeskim |
| pubmed-article:19067947 | lifeskim:mentions | umls-concept:C1312955 | lld:lifeskim |
| pubmed-article:19067947 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:19067947 | pubmed:dateCreated | 2009-5-12 | lld:pubmed |
| pubmed-article:19067947 | pubmed:abstractText | It is difficult to treat patients with acquired airway stenosis, and the quality of life of such patients is therefore lowered. We have suggested the application of photodynamic therapy (PDT) as a new treatment for airway stenosis and have determined the efficacy of PDT in animal disease models using a second-generation photosensitizer with reduced photosensitivity. An airway stenosis rabbit model induced by scraping of the tracheal mucosa was administered NPe6 (5 mg kg(-1)), and the stenotic lesion was irradiated with 670 nm light emitted from a cylindrical diffuser tip at 60 J cm(-2) under bronchoscopic monitoring. PDT using NPe6 improved airway stenosis (P = 0.043) and respiratory stridor. A significant prolongation of survival time was seen in the PDT-treated animals compared to that in the untreated animals (P = 0.025) and 44% of the treated animals achieved long-term survival (>60 days). In conclusion, PDT using NPe6 is effective for improvement in airway stenosis. | lld:pubmed |
| pubmed-article:19067947 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19067947 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19067947 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19067947 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19067947 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19067947 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19067947 | pubmed:issn | 0031-8655 | lld:pubmed |
| pubmed-article:19067947 | pubmed:author | pubmed-author:KikuchiMakoto... | lld:pubmed |
| pubmed-article:19067947 | pubmed:author | pubmed-author:MorimotoYujiY | lld:pubmed |
| pubmed-article:19067947 | pubmed:author | pubmed-author:FujitaMasanor... | lld:pubmed |
| pubmed-article:19067947 | pubmed:author | pubmed-author:MorimotoNorik... | lld:pubmed |
| pubmed-article:19067947 | pubmed:author | pubmed-author:MaeharaTadaak... | lld:pubmed |
| pubmed-article:19067947 | pubmed:author | pubmed-author:OzekiYuichiY | lld:pubmed |
| pubmed-article:19067947 | pubmed:author | pubmed-author:NakagishiYosh... | lld:pubmed |
| pubmed-article:19067947 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:19067947 | pubmed:volume | 85 | lld:pubmed |
| pubmed-article:19067947 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19067947 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19067947 | pubmed:pagination | 714-8 | lld:pubmed |
| pubmed-article:19067947 | pubmed:meshHeading | pubmed-meshheading:19067947... | lld:pubmed |
| pubmed-article:19067947 | pubmed:meshHeading | pubmed-meshheading:19067947... | lld:pubmed |
| pubmed-article:19067947 | pubmed:meshHeading | pubmed-meshheading:19067947... | lld:pubmed |
| pubmed-article:19067947 | pubmed:meshHeading | pubmed-meshheading:19067947... | lld:pubmed |
| pubmed-article:19067947 | pubmed:meshHeading | pubmed-meshheading:19067947... | lld:pubmed |
| pubmed-article:19067947 | pubmed:meshHeading | pubmed-meshheading:19067947... | lld:pubmed |
| pubmed-article:19067947 | pubmed:meshHeading | pubmed-meshheading:19067947... | lld:pubmed |
| pubmed-article:19067947 | pubmed:meshHeading | pubmed-meshheading:19067947... | lld:pubmed |
| pubmed-article:19067947 | pubmed:articleTitle | Amelioration of airway stenosis in rabbit models by photodynamic therapy with talaporfin sodium (NPe6). | lld:pubmed |
| pubmed-article:19067947 | pubmed:affiliation | Department of Medical Engineering, National Defense Medical College, Tokorozawa, Saitama, Japan. | lld:pubmed |
| pubmed-article:19067947 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19067947 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
