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pubmed-article:19058909pubmed:abstractTextWe herein report the first case of progressive perianeurysmal edema preceding the rupture of a small saccular aneurysm, without any intervention or intraluminal thrombosis. A 71-year-old woman was incidentally noted to have a cerebral aneurysm (5mm in diameter) at the lower basilar artery. Twelve months later, magnetic resonance (MR) imaging showed a T2-elongated area around a dome of the aneurysm buried in the brain stem, suggesting perianeurysmal edema formation. Interestingly, the edema progressed with the formation of a bleb, in addition to an increase in size of the aneurysm over the following 3-year period. The aneurysm eventually ruptured as a brain stem hemorrhage without any subarachnoid clots 3 days after the final check-up with MR imaging, by which a significant increase of edema formation with an increase in size of the aneurysm and a marked expansion of the bleb was observed. These findings raise the possibility that bleb formation and an enlargement of a small cerebral aneurysm might also be associated with perianeurysmal edema and a subsequent aneurysmal rupture. In addition to the pulsatile flow and/or compression from the expanded aneurysm, local inflammation in the aneurysm wall may play an important role in such edema formation.lld:pubmed
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pubmed-article:19058909pubmed:authorpubmed-author:NagataIzumiIlld:pubmed
pubmed-article:19058909pubmed:authorpubmed-author:KitagawaNaoki...lld:pubmed
pubmed-article:19058909pubmed:authorpubmed-author:HayashiKentar...lld:pubmed
pubmed-article:19058909pubmed:authorpubmed-author:TsutsumiKeisu...lld:pubmed
pubmed-article:19058909pubmed:authorpubmed-author:HiuTakeshiTlld:pubmed
pubmed-article:19058909pubmed:authorpubmed-author:SuyamaKazuhik...lld:pubmed
pubmed-article:19058909pubmed:authorpubmed-author:UjifukuKentaKlld:pubmed
pubmed-article:19058909pubmed:authorpubmed-author:YasunagaAkioAlld:pubmed
pubmed-article:19058909pubmed:issnTypeElectroniclld:pubmed
pubmed-article:19058909pubmed:volume111lld:pubmed
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pubmed-article:19058909pubmed:pagination216-9lld:pubmed
pubmed-article:19058909pubmed:dateRevised2009-10-14lld:pubmed
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pubmed-article:19058909pubmed:year2009lld:pubmed
pubmed-article:19058909pubmed:articleTitleProgressive perianeurysmal edema preceding the rupture of a small basilar artery aneurysm.lld:pubmed
pubmed-article:19058909pubmed:affiliationDepartment of Neurosurgery, Nagasaki University Graduate School of Biomedical Sciences, Nagasaki, Japan. thiu-nagasaki@umin.ac.jplld:pubmed
pubmed-article:19058909pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19058909pubmed:publicationTypeCase Reportslld:pubmed