| pubmed-article:19020909 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19020909 | lifeskim:mentions | umls-concept:C0026912 | lld:lifeskim |
| pubmed-article:19020909 | lifeskim:mentions | umls-concept:C0003320 | lld:lifeskim |
| pubmed-article:19020909 | lifeskim:mentions | umls-concept:C0021745 | lld:lifeskim |
| pubmed-article:19020909 | lifeskim:mentions | umls-concept:C1609538 | lld:lifeskim |
| pubmed-article:19020909 | lifeskim:mentions | umls-concept:C0205177 | lld:lifeskim |
| pubmed-article:19020909 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:19020909 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:19020909 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:19020909 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:19020909 | lifeskim:mentions | umls-concept:C0392762 | lld:lifeskim |
| pubmed-article:19020909 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:19020909 | pubmed:dateCreated | 2009-5-26 | lld:pubmed |
| pubmed-article:19020909 | pubmed:abstractText | The objective was to compare the quantitative T-cell responses measured by the commercial interferon-gamma (IFNgamma) release assays (IGRAs) in active and latent tuberculosis (TB) states. T-cell responses of culture-proven TB cases were compared with those of contacts with positive IGRA results and tuberculin skin tests >or= 15 mm. T-SPOT.TB results in 270 active TB cases and 183 community contacts showed the median spot-forming cells (SFCs) above negative control/2.5 x 10(5) peripheral blood mononuclear cells to be 27 (-1 to 203) vs 10 (-2 to 174) in response to ESAT-6 (p < 0.001); and 37 (0 to 293) vs 13 (0 to 225) to CFP-10 (p < 0.001). The median IFNgamma levels (antigen minus nil control) as measured by QuantiFERON-TB Gold In-tube in 270 cases and 142 contacts in congregate settings was 2.3 IU/ml (-0.58 to 31.44) vs 1.7 IU/ml (0.35 to 26.51, p = 0.98). Quantitative T-cell responses as measured by the T-SPOT.TB may indicate mycobacterial burden and disease activity, but cannot be used to discriminate active from latent TB. | lld:pubmed |
| pubmed-article:19020909 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19020909 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19020909 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19020909 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19020909 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19020909 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19020909 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:19020909 | pubmed:issn | 1435-4373 | lld:pubmed |
| pubmed-article:19020909 | pubmed:author | pubmed-author:WangY TYT | lld:pubmed |
| pubmed-article:19020909 | pubmed:author | pubmed-author:DixL PLP | lld:pubmed |
| pubmed-article:19020909 | pubmed:author | pubmed-author:CheeC B ECB | lld:pubmed |
| pubmed-article:19020909 | pubmed:author | pubmed-author:BarkhamT M... | lld:pubmed |
| pubmed-article:19020909 | pubmed:author | pubmed-author:KhinmarK WKW | lld:pubmed |
| pubmed-article:19020909 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19020909 | pubmed:volume | 28 | lld:pubmed |
| pubmed-article:19020909 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19020909 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19020909 | pubmed:pagination | 667-70 | lld:pubmed |
| pubmed-article:19020909 | pubmed:meshHeading | pubmed-meshheading:19020909... | lld:pubmed |
| pubmed-article:19020909 | pubmed:meshHeading | pubmed-meshheading:19020909... | lld:pubmed |
| pubmed-article:19020909 | pubmed:meshHeading | pubmed-meshheading:19020909... | lld:pubmed |
| pubmed-article:19020909 | pubmed:meshHeading | pubmed-meshheading:19020909... | lld:pubmed |
| pubmed-article:19020909 | pubmed:meshHeading | pubmed-meshheading:19020909... | lld:pubmed |
| pubmed-article:19020909 | pubmed:meshHeading | pubmed-meshheading:19020909... | lld:pubmed |
| pubmed-article:19020909 | pubmed:meshHeading | pubmed-meshheading:19020909... | lld:pubmed |
| pubmed-article:19020909 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19020909 | pubmed:articleTitle | Quantitative T-cell interferon-gamma responses to Mycobacterium tuberculosis-specific antigens in active and latent tuberculosis. | lld:pubmed |
| pubmed-article:19020909 | pubmed:affiliation | Singapore Tuberculosis Control Unit, Tan Tock Seng Hospital, Singapore, Singapore. cynthia_chee@ttsh.com.sg | lld:pubmed |
| pubmed-article:19020909 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19020909 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:19020909 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19020909 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:19020909 | lld:pubmed |
