| pubmed-article:19016796 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:19016796 | lifeskim:mentions | umls-concept:C0444626 | lld:lifeskim |
| pubmed-article:19016796 | lifeskim:mentions | umls-concept:C0060926 | lld:lifeskim |
| pubmed-article:19016796 | lifeskim:mentions | umls-concept:C0022203 | lld:lifeskim |
| pubmed-article:19016796 | lifeskim:mentions | umls-concept:C1572759 | lld:lifeskim |
| pubmed-article:19016796 | lifeskim:mentions | umls-concept:C0376315 | lld:lifeskim |
| pubmed-article:19016796 | lifeskim:mentions | umls-concept:C1882417 | lld:lifeskim |
| pubmed-article:19016796 | pubmed:issue | 1 | lld:pubmed |
| pubmed-article:19016796 | pubmed:dateCreated | 2009-1-20 | lld:pubmed |
| pubmed-article:19016796 | pubmed:abstractText | Gabapentin, a widely used antiepileptic drug, crystallizes in multiple polymorphic forms. A new crystal form of gabapentin monohydrate in the space group Pbca is reported and the packing arrangement compared with that of a previously reported polymorph in the space group P2(1)/c [Ibers, J.A. (2001) Acta Crystallogr; C57:641]. Gabapentin polymorphs can also occur from a selection of one of the two distinct chair forms of the 1,1-disubstituted cyclohexane. Crystal structures of the E and Z isomers of 4-tert-butylgabapentin provide models for analyzing anticipated packing modes in the conformational isomers of gabapentin. The E isomer crystallized in the space group Pca2(1), while the Z isomer crystallized in the space group P2(1)/c. The crystal structure of E-4-tert-butylgabapentin provides the only example of a structure in a non-centrosymmetric space group. Crystal structures of the hydrochloride and hydrobromide salts of 4-tert-butyl derivatives are reported. The results suggest that for gabapentin, a large 'polymorph-space' may be anticipated, in view of the multiple conformational states that are accessible to the molecule. | lld:pubmed |
| pubmed-article:19016796 | pubmed:language | eng | lld:pubmed |
| pubmed-article:19016796 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19016796 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:19016796 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19016796 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19016796 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19016796 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19016796 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:19016796 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:19016796 | pubmed:month | Jan | lld:pubmed |
| pubmed-article:19016796 | pubmed:issn | 1747-0285 | lld:pubmed |
| pubmed-article:19016796 | pubmed:author | pubmed-author:BalaramPadman... | lld:pubmed |
| pubmed-article:19016796 | pubmed:author | pubmed-author:AnandaKuppann... | lld:pubmed |
| pubmed-article:19016796 | pubmed:author | pubmed-author:AravindaSubra... | lld:pubmed |
| pubmed-article:19016796 | pubmed:author | pubmed-author:ShamalaNaraya... | lld:pubmed |
| pubmed-article:19016796 | pubmed:author | pubmed-author:VasudevPrema... | lld:pubmed |
| pubmed-article:19016796 | pubmed:author | pubmed-author:NagarajanKupp... | lld:pubmed |
| pubmed-article:19016796 | pubmed:author | pubmed-author:VeenaShettyke... | lld:pubmed |
| pubmed-article:19016796 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:19016796 | pubmed:volume | 73 | lld:pubmed |
| pubmed-article:19016796 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:19016796 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:19016796 | pubmed:pagination | 83-96 | lld:pubmed |
| pubmed-article:19016796 | pubmed:meshHeading | pubmed-meshheading:19016796... | lld:pubmed |
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| pubmed-article:19016796 | pubmed:meshHeading | pubmed-meshheading:19016796... | lld:pubmed |
| pubmed-article:19016796 | pubmed:year | 2009 | lld:pubmed |
| pubmed-article:19016796 | pubmed:articleTitle | Crystal structures of a new polymorphic form of gabapentin monohydrate and the e and z isomers of 4-tertiarybutylgabapentin. | lld:pubmed |
| pubmed-article:19016796 | pubmed:affiliation | Department of Physics, Indian Institute of Science, Bangalore 560012, India. | lld:pubmed |
| pubmed-article:19016796 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:19016796 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
