pubmed-article:1900950 | rdf:type | pubmed:Citation | lld:pubmed |
pubmed-article:1900950 | lifeskim:mentions | umls-concept:C0025936 | lld:lifeskim |
pubmed-article:1900950 | lifeskim:mentions | umls-concept:C0004561 | lld:lifeskim |
pubmed-article:1900950 | lifeskim:mentions | umls-concept:C0039194 | lld:lifeskim |
pubmed-article:1900950 | lifeskim:mentions | umls-concept:C0004359 | lld:lifeskim |
pubmed-article:1900950 | lifeskim:mentions | umls-concept:C0205263 | lld:lifeskim |
pubmed-article:1900950 | pubmed:issue | 4998 | lld:pubmed |
pubmed-article:1900950 | pubmed:dateCreated | 1991-4-23 | lld:pubmed |
pubmed-article:1900950 | pubmed:abstractText | Self-tolerance to a transgene-encoded protein, hen egg lysozyme, was examined in the T and B cell repertoires of a series of lines of transgenic mice that expressed different serum concentrations of soluble lysozyme. T cells were tolerant in all lines in which lysozyme was expressed irrespective of the antigen concentration, whereas B cell tolerance did not occur when the serum lysozyme concentration was less than 1.5 nanograms per milliliter (0.1 nM). Induction of elevated transgene expression could restore B cell tolerance. These findings support the hypothesis that autoimmune disease may in some instances arise through a bypass of T cell tolerance. | lld:pubmed |
pubmed-article:1900950 | pubmed:language | eng | lld:pubmed |
pubmed-article:1900950 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1900950 | pubmed:citationSubset | IM | lld:pubmed |
pubmed-article:1900950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1900950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1900950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1900950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1900950 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:1900950 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:1900950 | pubmed:month | Mar | lld:pubmed |
pubmed-article:1900950 | pubmed:issn | 0036-8075 | lld:pubmed |
pubmed-article:1900950 | pubmed:author | pubmed-author:BastenAA | lld:pubmed |
pubmed-article:1900950 | pubmed:author | pubmed-author:Pritchard-Bri... | lld:pubmed |
pubmed-article:1900950 | pubmed:author | pubmed-author:LoblayR HRH | lld:pubmed |
pubmed-article:1900950 | pubmed:author | pubmed-author:AndersonT ATA | lld:pubmed |
pubmed-article:1900950 | pubmed:author | pubmed-author:AdelsteinSS | lld:pubmed |
pubmed-article:1900950 | pubmed:author | pubmed-author:GoodnowC CCC | lld:pubmed |
pubmed-article:1900950 | pubmed:author | pubmed-author:CrosbieJJ | lld:pubmed |
pubmed-article:1900950 | pubmed:author | pubmed-author:GammonGG | lld:pubmed |
pubmed-article:1900950 | pubmed:issnType | Print | lld:pubmed |
pubmed-article:1900950 | pubmed:day | 8 | lld:pubmed |
pubmed-article:1900950 | pubmed:volume | 251 | lld:pubmed |
pubmed-article:1900950 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:1900950 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:1900950 | pubmed:pagination | 1223-5 | lld:pubmed |
pubmed-article:1900950 | pubmed:dateRevised | 2007-3-19 | lld:pubmed |
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pubmed-article:1900950 | pubmed:year | 1991 | lld:pubmed |
pubmed-article:1900950 | pubmed:articleTitle | Induction of self-tolerance in T cells but not B cells of transgenic mice expressing little self antigen. | lld:pubmed |
pubmed-article:1900950 | pubmed:affiliation | Cell Biology and Metabolism Branch, National Institute of Child Health and Human Development, National Institutes of Health, Bethesda, MD 20892. | lld:pubmed |
pubmed-article:1900950 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:1900950 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
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