Linked Life Data

19003934

Source:http://linkedlifedata.com/resource/pubmed/id/19003934

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:19003934rdf:typepubmed:Citationlld:pubmed
pubmed-article:19003934lifeskim:mentionsumls-concept:C0020971lld:lifeskim
pubmed-article:19003934lifeskim:mentionsumls-concept:C0086418lld:lifeskim
pubmed-article:19003934lifeskim:mentionsumls-concept:C0007634lld:lifeskim
pubmed-article:19003934lifeskim:mentionsumls-concept:C0206694lld:lifeskim
pubmed-article:19003934lifeskim:mentionsumls-concept:C0021853lld:lifeskim
pubmed-article:19003934lifeskim:mentionsumls-concept:C1332688lld:lifeskim
pubmed-article:19003934lifeskim:mentionsumls-concept:C1425042lld:lifeskim
pubmed-article:19003934lifeskim:mentionsumls-concept:C0205263lld:lifeskim
pubmed-article:19003934lifeskim:mentionsumls-concept:C1553423lld:lifeskim
pubmed-article:19003934lifeskim:mentionsumls-concept:C0205373lld:lifeskim
pubmed-article:19003934pubmed:issue12lld:pubmed
pubmed-article:19003934pubmed:dateCreated2008-12-2lld:pubmed
pubmed-article:19003934pubmed:abstractTextOrgan-specific homing of lymphoid cells depends on the expression of tissue-specific adhesion molecules and production of specific chemokines. CCL25 (TECK) and CCL28 (MEC) have been reported to direct circulating memory/effector B cells to mucosal tissues. Here, we examined if differential responsiveness to mucosal and systemic chemokines could explain the differential migration pattern of circulating human antibody-secreting cells (ASC), induced by mucosal and systemic immunization. There was a robust migration of specific IgA- and IgM-ASC induced by Salmonella vaccination toward the mucosal chemokines CCL25 and CCL28. In contrast, tetanus-specific ASC migrated to the systemic chemokine CXCL12 (SDF-1alpha) and showed no response to CCL25 or CCL28, not even tetanus-specific IgA-ASC. Cell sorting experiments demonstrated that Salmonella-specific ASC co-expressed CCR9 and CCR10. Our results show that induction site, rather than isotype commitment, determines the chemokine responsiveness and migration pattern of human effector B cells.lld:pubmed
pubmed-article:19003934pubmed:commentsCorrectionshttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19003934pubmed:languageenglld:pubmed
pubmed-article:19003934pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19003934pubmed:citationSubsetIMlld:pubmed
pubmed-article:19003934pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19003934pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19003934pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19003934pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19003934pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19003934pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19003934pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19003934pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19003934pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:19003934pubmed:statusMEDLINElld:pubmed
pubmed-article:19003934pubmed:monthDeclld:pubmed
pubmed-article:19003934pubmed:issn1521-4141lld:pubmed
pubmed-article:19003934pubmed:authorpubmed-author:LundinSamuel...lld:pubmed
pubmed-article:19003934pubmed:authorpubmed-author:Quiding-Järbr...lld:pubmed
pubmed-article:19003934pubmed:authorpubmed-author:SundströmPatr...lld:pubmed
pubmed-article:19003934pubmed:authorpubmed-author:NilssonLars-A...lld:pubmed
pubmed-article:19003934pubmed:issnTypeElectroniclld:pubmed
pubmed-article:19003934pubmed:volume38lld:pubmed
pubmed-article:19003934pubmed:ownerNLMlld:pubmed
pubmed-article:19003934pubmed:authorsCompleteYlld:pubmed
pubmed-article:19003934pubmed:pagination3327-38lld:pubmed
pubmed-article:19003934pubmed:dateRevised2010-2-24lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:meshHeadingpubmed-meshheading:19003934...lld:pubmed
pubmed-article:19003934pubmed:year2008lld:pubmed
pubmed-article:19003934pubmed:articleTitleHuman IgA-secreting cells induced by intestinal, but not systemic, immunization respond to CCL25 (TECK) and CCL28 (MEC).lld:pubmed
pubmed-article:19003934pubmed:affiliationDepartment of Microbiology and Immunology, Göteborg University Vaccine Research Institute, The Sahlgrenska Academy, The University of Gothenburg, Gothenburg, Sweden.lld:pubmed
pubmed-article:19003934pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:19003934pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed
entrez-gene:6370entrezgene:pubmedpubmed-article:19003934lld:entrezgene
entrez-gene:56477entrezgene:pubmedpubmed-article:19003934lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:19003934lld:entrezgene
http://linkedlifedata.com/r...entrezgene:pubmedpubmed-article:19003934lld:entrezgene