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pubmed-article:19003636pubmed:abstractTextMicroparticles (MP) are pro-coagulant vesicles derived from various cells. Evidence is accumulating that MP are of pathophysiological relevance in autoimmune, cardiovascular, and thromboembolic diseases and inflammatory disorders. Therefore, their role in the development of preeclampsia was investigated and MP from preeclamptic patients influenced endothelial-dependent vasodilatation. Knowledge about changes in circulating MP numbers during pregnancy and preeclampsia is lacking. We determined this longitudinally and investigated whether these numbers related to the severity of preeclampsia.lld:pubmed
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pubmed-article:19003636pubmed:authorpubmed-author:BoerKeesKlld:pubmed
pubmed-article:19003636pubmed:authorpubmed-author:NieuwlandRien...lld:pubmed
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pubmed-article:19003636pubmed:authorpubmed-author:HauChi MCMlld:pubmed
pubmed-article:19003636pubmed:authorpubmed-author:LokChristine...lld:pubmed
pubmed-article:19003636pubmed:authorpubmed-author:Van Der...lld:pubmed
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pubmed-article:19003636pubmed:volume27lld:pubmed
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pubmed-article:19003636pubmed:pagination344-60lld:pubmed
pubmed-article:19003636pubmed:dateRevised2009-5-12lld:pubmed
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pubmed-article:19003636pubmed:year2008lld:pubmed
pubmed-article:19003636pubmed:articleTitleChanges in microparticle numbers and cellular origin during pregnancy and preeclampsia.lld:pubmed
pubmed-article:19003636pubmed:affiliationDepartment of Obstetrics and Gynaecology, Academic Medical Center, Amsterdam, The Netherlands. c.a.lok@amc.uva.nllld:pubmed
pubmed-article:19003636pubmed:publicationTypeJournal Articlelld:pubmed
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