| pubmed-article:18981407 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18981407 | lifeskim:mentions | umls-concept:C0035820 | lld:lifeskim |
| pubmed-article:18981407 | lifeskim:mentions | umls-concept:C0024660 | lld:lifeskim |
| pubmed-article:18981407 | lifeskim:mentions | umls-concept:C1167395 | lld:lifeskim |
| pubmed-article:18981407 | lifeskim:mentions | umls-concept:C0105770 | lld:lifeskim |
| pubmed-article:18981407 | lifeskim:mentions | umls-concept:C0040648 | lld:lifeskim |
| pubmed-article:18981407 | lifeskim:mentions | umls-concept:C1704675 | lld:lifeskim |
| pubmed-article:18981407 | lifeskim:mentions | umls-concept:C0162610 | lld:lifeskim |
| pubmed-article:18981407 | pubmed:issue | 45 | lld:pubmed |
| pubmed-article:18981407 | pubmed:dateCreated | 2008-11-13 | lld:pubmed |
| pubmed-article:18981407 | pubmed:abstractText | We used the model nematode Caenorhabditis elegans infected with the human pathogen Staphylococcus aureus to identify components of epithelial immunity. Transcriptional profiling and reverse genetic analysis revealed that mutation of the C. elegans beta-catenin homolog bar-1 or the downstream homeobox gene egl-5 results in a defective response and hypersensitivity to S. aureus infection. Epistasis analysis showed that bar-1 and egl-5 function in parallel to previously described C. elegans immune-response pathways. Overexpression of human homologs of egl-5 modulated NF-kappaB-dependent TLR2 signaling in epithelial cells. These data suggest that beta-catenin and homeobox genes play an important and conserved role in innate immune defense. | lld:pubmed |
| pubmed-article:18981407 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:commentsCorrections | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18981407 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18981407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18981407 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18981407 | pubmed:month | Nov | lld:pubmed |
| pubmed-article:18981407 | pubmed:issn | 1091-6490 | lld:pubmed |
| pubmed-article:18981407 | pubmed:author | pubmed-author:XavierRamnik... | lld:pubmed |
| pubmed-article:18981407 | pubmed:author | pubmed-author:AusubelFreder... | lld:pubmed |
| pubmed-article:18981407 | pubmed:author | pubmed-author:NgAylwinA | lld:pubmed |
| pubmed-article:18981407 | pubmed:author | pubmed-author:IrazoquiJavie... | lld:pubmed |
| pubmed-article:18981407 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18981407 | pubmed:day | 11 | lld:pubmed |
| pubmed-article:18981407 | pubmed:volume | 105 | lld:pubmed |
| pubmed-article:18981407 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18981407 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18981407 | pubmed:pagination | 17469-74 | lld:pubmed |
| pubmed-article:18981407 | pubmed:dateRevised | 2011-10-11 | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:meshHeading | pubmed-meshheading:18981407... | lld:pubmed |
| pubmed-article:18981407 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18981407 | pubmed:articleTitle | Role for beta-catenin and HOX transcription factors in Caenorhabditis elegans and mammalian host epithelial-pathogen interactions. | lld:pubmed |
| pubmed-article:18981407 | pubmed:affiliation | Department of Genetics, Harvard Medical School, and Center for Computational and Integrative Biology, Massachusetts General Hospital, Boston, MA 02114, USA. | lld:pubmed |
| pubmed-article:18981407 | pubmed:publicationType | Journal Article | lld:pubmed |
