| pubmed-article:18979628 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18979628 | lifeskim:mentions | umls-concept:C0206131 | lld:lifeskim |
| pubmed-article:18979628 | lifeskim:mentions | umls-concept:C0334227 | lld:lifeskim |
| pubmed-article:18979628 | lifeskim:mentions | umls-concept:C0623362 | lld:lifeskim |
| pubmed-article:18979628 | lifeskim:mentions | umls-concept:C0178874 | lld:lifeskim |
| pubmed-article:18979628 | lifeskim:mentions | umls-concept:C1511572 | lld:lifeskim |
| pubmed-article:18979628 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:18979628 | pubmed:dateCreated | 2008-11-3 | lld:pubmed |
| pubmed-article:18979628 | pubmed:abstractText | This brief review focuses on the emerging role of matrix metalloproteinase 11 (MMP-11) in cancer progression. It has recently been shown that MMP-11 is induced in adipose tissue by cancer cells as they invade their surrounding environment. MMP-11 negatively regulates adipogenesis by reducing pre-adipocyte differentiation and reversing mature adipocyte differentiation. Adipocyte dedifferentiation in turn leads to the accumulation of nonmalignant peritumoral fibroblast-like cells, which favor cancer cell survival and tumor progression. This MMP-11-mediated bi-directional cross-talk between invading cancer cells and adjacent adipocytes/pre-adipocytes highlights the central role that MMP-11 plays during tumor desmoplasia and represents a molecular link between obesity and cancer. | lld:pubmed |
| pubmed-article:18979628 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18979628 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18979628 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18979628 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18979628 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18979628 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:18979628 | pubmed:issn | 1431-6730 | lld:pubmed |
| pubmed-article:18979628 | pubmed:author | pubmed-author:RioMarie-Chri... | lld:pubmed |
| pubmed-article:18979628 | pubmed:author | pubmed-author:MotrescuElena... | lld:pubmed |
| pubmed-article:18979628 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18979628 | pubmed:volume | 389 | lld:pubmed |
| pubmed-article:18979628 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18979628 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18979628 | pubmed:pagination | 1037-41 | lld:pubmed |
| pubmed-article:18979628 | pubmed:meshHeading | pubmed-meshheading:18979628... | lld:pubmed |
| pubmed-article:18979628 | pubmed:meshHeading | pubmed-meshheading:18979628... | lld:pubmed |
| pubmed-article:18979628 | pubmed:meshHeading | pubmed-meshheading:18979628... | lld:pubmed |
| pubmed-article:18979628 | pubmed:meshHeading | pubmed-meshheading:18979628... | lld:pubmed |
| pubmed-article:18979628 | pubmed:meshHeading | pubmed-meshheading:18979628... | lld:pubmed |
| pubmed-article:18979628 | pubmed:meshHeading | pubmed-meshheading:18979628... | lld:pubmed |
| pubmed-article:18979628 | pubmed:meshHeading | pubmed-meshheading:18979628... | lld:pubmed |
| pubmed-article:18979628 | pubmed:meshHeading | pubmed-meshheading:18979628... | lld:pubmed |
| pubmed-article:18979628 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18979628 | pubmed:articleTitle | Cancer cells, adipocytes and matrix metalloproteinase 11: a vicious tumor progression cycle. | lld:pubmed |
| pubmed-article:18979628 | pubmed:affiliation | Institut de Génétique et de Biologie Moléculaire et Cellulaire, CNRS UMR 7104, INSERM U596, ULP, C.U. de Strasbourg, BP 10142, F-67404 Illkirch Cedex, France. | lld:pubmed |
| pubmed-article:18979628 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18979628 | pubmed:publicationType | Review | lld:pubmed |
| pubmed-article:18979628 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18979628 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18979628 | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18979628 | lld:pubmed |
