|
rdf:type |
|
|
lifeskim:mentions |
umls-concept:C0017638,
umls-concept:C0038250,
umls-concept:C0205282,
umls-concept:C0443252,
umls-concept:C0449258,
umls-concept:C0521158,
umls-concept:C0580822,
umls-concept:C0677930,
umls-concept:C1314677,
umls-concept:C1533691,
umls-concept:C1547300,
umls-concept:C1548760,
umls-concept:C1550594
|
|
pubmed:dateCreated |
2008-11-18
|
|
pubmed:abstractText |
Despite the advances made during decades of research, the mechanisms by which glioma is initiated and established remain elusive. The discovery of glioma stem cells (GSCs) may help to elucidate the processes of gliomagenesis with respect to their phenotype, differentiation and tumorigenic capacity during initiation and progression. Research on GSCs is still in its infancy, so no definitive conclusions about their role can yet be drawn. To understand the biology of GSCs fully, it is highly desirable to establish permanent and biologically stable GSC lines.
|
|
pubmed:commentsCorrections |
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-10416987,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-11689955,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-12084351,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-12203386,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-14522905,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-14603439,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-14645703,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-14711994,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-14735193,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-15077152,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-15095300,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-15157306,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-15254063,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-15298715,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-15466194,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-1553558,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-15549107,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-15558011,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-15831234,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-15925587,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-15956643,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-16120861,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-16123777,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-16196299,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-16357533,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-16373498,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-16617102,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-16630134,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-16723989,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-16733204,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-17088899,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-17440081,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-17483311,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-17673180,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-18037961,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-2009534,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-3477813,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-9072974,
http://linkedlifedata.com/resource/pubmed/commentcorrection/18940013-9393738
|
|
pubmed:language |
eng
|
|
pubmed:journal |
|
|
pubmed:citationSubset |
IM
|
|
pubmed:chemical |
|
|
pubmed:status |
MEDLINE
|
|
pubmed:issn |
1471-2407
|
|
pubmed:author |
|
|
pubmed:issnType |
Electronic
|
|
pubmed:volume |
8
|
|
pubmed:owner |
NLM
|
|
pubmed:authorsComplete |
Y
|
|
pubmed:pagination |
304
|
|
pubmed:dateRevised |
2009-11-18
|
|
pubmed:meshHeading |
pubmed-meshheading:18940013-Animals,
pubmed-meshheading:18940013-Antigens, CD,
pubmed-meshheading:18940013-Astrocytoma,
pubmed-meshheading:18940013-Brain Neoplasms,
pubmed-meshheading:18940013-Cell Differentiation,
pubmed-meshheading:18940013-Cell Growth Processes,
pubmed-meshheading:18940013-Comparative Genomic Hybridization,
pubmed-meshheading:18940013-Disease Progression,
pubmed-meshheading:18940013-Ependymoma,
pubmed-meshheading:18940013-Female,
pubmed-meshheading:18940013-Flow Cytometry,
pubmed-meshheading:18940013-Gene Dosage,
pubmed-meshheading:18940013-Glioma,
pubmed-meshheading:18940013-Glycoproteins,
pubmed-meshheading:18940013-Humans,
pubmed-meshheading:18940013-Mice,
pubmed-meshheading:18940013-Mice, Nude,
pubmed-meshheading:18940013-Microscopy, Electron, Transmission,
pubmed-meshheading:18940013-Middle Aged,
pubmed-meshheading:18940013-Neoplasm Recurrence, Local,
pubmed-meshheading:18940013-Neoplasm Transplantation,
pubmed-meshheading:18940013-Neoplastic Stem Cells,
pubmed-meshheading:18940013-Peptides,
pubmed-meshheading:18940013-Transplantation, Heterologous,
pubmed-meshheading:18940013-Tumor Cells, Cultured
|
|
pubmed:year |
2008
|
|
pubmed:articleTitle |
Glioma stem cells are more aggressive in recurrent tumors with malignant progression than in the primary tumor, and both can be maintained long-term in vitro.
|
|
pubmed:affiliation |
Department of Neurosurgery and Brain Tumor Research Laboratory, Second Affiliated Hospital of Suzhou University, Suzhou 215004, PR China. hq1936@yahoo.com.cn
|
|
pubmed:publicationType |
Journal Article,
Research Support, Non-U.S. Gov't
|
