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pubmed-article:18854233pubmed:abstractTextThe fungal pathogen Cryptococcus neoformans has three major virulence factors: growth at 37 degrees C, capsule synthesis, and melanin formation. Recently in Cell, Liu et al. (2008) employed signature tagged mutagenesis to systematically identify virulence genes. Remarkably, mutations in many of these genes did not influence the major virulence traits.lld:pubmed
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pubmed-article:18854233pubmed:articleTitleBeyond the big three: systematic analysis of virulence factors in Cryptococcus neoformans.lld:pubmed
pubmed-article:18854233pubmed:affiliationMichael Smith Laboratories, Department of Microbiology and Immunology, University of British Columbia, Vancouver, BC V6T 1Z4, Canada.lld:pubmed
pubmed-article:18854233pubmed:publicationTypeJournal Articlelld:pubmed