Pancreatic cancer is a highly invasive malignancy. Ezrin, a plasma membrane-cytoskeletal linker protein, is associated with the invasive behaviour of cancers. The purpose of this study was to elucidate a possible molecular mechanism for the invasive phenotype.
Centre for Tumour Biology, Institute of Cancer and CR-UK Clinical Centre, Barts & The London School of Medicine & Dentistry, John Vane Science Centre, London, UK. hemant.kocher@cancer.org.uk