| pubmed-article:18840968 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18840968 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:18840968 | lifeskim:mentions | umls-concept:C0007427 | lld:lifeskim |
| pubmed-article:18840968 | lifeskim:mentions | umls-concept:C0037925 | lld:lifeskim |
| pubmed-article:18840968 | lifeskim:mentions | umls-concept:C0332679 | lld:lifeskim |
| pubmed-article:18840968 | lifeskim:mentions | umls-concept:C1441616 | lld:lifeskim |
| pubmed-article:18840968 | lifeskim:mentions | umls-concept:C0175722 | lld:lifeskim |
| pubmed-article:18840968 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:18840968 | pubmed:issue | 9 | lld:pubmed |
| pubmed-article:18840968 | pubmed:dateCreated | 2008-10-8 | lld:pubmed |
| pubmed-article:18840968 | pubmed:abstractText | This study examined the temporal expression of cathepsin D protein and its cellular localization in the spinal cords of rats after a clip compression injury to determine the involvement of cathepsin D in spinal cord injury (SCI). Western blot analysis showed a significant increase in the approximately 31-kDa active form of cathepsin D on days 4 and 7 after the SCI, while the level of the approximately 44-kDa inactive form remained relatively unchanged. Immunohistochemistry revealed cathepsin D with constitutive localization in most neurons and some gliocytes in the normal spinal cord to be intensely immuno-detected primarily in CD68-positive activated macrophages/microglia in the SCI lesions. Overall, these findings suggest that cathepsin D plays an important role in the phagocytosis and lysosomal activation of macrophages/microglia during the central nervous system inflammation caused by trauma. | lld:pubmed |
| pubmed-article:18840968 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18840968 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18840968 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18840968 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18840968 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18840968 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:18840968 | pubmed:issn | 0916-7250 | lld:pubmed |
| pubmed-article:18840968 | pubmed:author | pubmed-author:MoonChangjong... | lld:pubmed |
| pubmed-article:18840968 | pubmed:author | pubmed-author:AhnMeejungM | lld:pubmed |
| pubmed-article:18840968 | pubmed:author | pubmed-author:ShinTaekyunT | lld:pubmed |
| pubmed-article:18840968 | pubmed:author | pubmed-author:LeeYongdukY | lld:pubmed |
| pubmed-article:18840968 | pubmed:author | pubmed-author:SimKi-BumKB | lld:pubmed |
| pubmed-article:18840968 | pubmed:author | pubmed-author:KimMoon DooMD | lld:pubmed |
| pubmed-article:18840968 | pubmed:author | pubmed-author:KimHeechulH | lld:pubmed |
| pubmed-article:18840968 | pubmed:author | pubmed-author:LeeTae-KiTK | lld:pubmed |
| pubmed-article:18840968 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18840968 | pubmed:volume | 70 | lld:pubmed |
| pubmed-article:18840968 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18840968 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18840968 | pubmed:pagination | 937-41 | lld:pubmed |
| pubmed-article:18840968 | pubmed:meshHeading | pubmed-meshheading:18840968... | lld:pubmed |
| pubmed-article:18840968 | pubmed:meshHeading | pubmed-meshheading:18840968... | lld:pubmed |
| pubmed-article:18840968 | pubmed:meshHeading | pubmed-meshheading:18840968... | lld:pubmed |
| pubmed-article:18840968 | pubmed:meshHeading | pubmed-meshheading:18840968... | lld:pubmed |
| pubmed-article:18840968 | pubmed:meshHeading | pubmed-meshheading:18840968... | lld:pubmed |
| pubmed-article:18840968 | pubmed:meshHeading | pubmed-meshheading:18840968... | lld:pubmed |
| pubmed-article:18840968 | pubmed:meshHeading | pubmed-meshheading:18840968... | lld:pubmed |
| pubmed-article:18840968 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18840968 | pubmed:articleTitle | Immunohistochemical study of cathepsin D in the spinal cords of rats with clip compression injury. | lld:pubmed |
| pubmed-article:18840968 | pubmed:affiliation | Department of Veterinary Anatomy, College of Veterinary Medicine and Veterinary Medical Research Center, Chonnam National University, Gwangju, South Korea. | lld:pubmed |
| pubmed-article:18840968 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18840968 | pubmed:publicationType | Comparative Study | lld:pubmed |
| pubmed-article:18840968 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| entrez-gene:171293 | entrezgene:pubmed | pubmed-article:18840968 | lld:entrezgene |
| http://linkedlifedata.com/r... | entrezgene:pubmed | pubmed-article:18840968 | lld:entrezgene |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18840968 | lld:pubmed |
