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pubmed-article:18784242pubmed:abstractTextVery few data have been reported on the epidemiology and clinical features of leprosy reactions in non-endemic settings. We performed a retrospective descriptive analysis to define the frequency and features of Type 1 and Type 2 leprosy reactions in a cohort of patients followed at a US travel and tropical medicine clinic in a 5-year period. We identified that leprosy reactions presented in 10/14 (71.4%) patients with leprosy seen at our clinic. We identified that leprosy reactions occur frequently among patients living in non-endemic areas and may occur before the initiation of multi-drug therapy (MDT), during MDT, or even years after completion of therapy and may produce significant neurologic sequelae. This group of patients needs long-term clinical monitoring even after completion of MDT because of the need to continue either anti-inflammatory therapy, presence of severe neurologic sequelae after reactions, or the potential occurrence of late leprosy reactions.lld:pubmed
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pubmed-article:18784242pubmed:articleTitleFive-year experience with type 1 and type 2 reactions in Hansen disease at a US travel clinic.lld:pubmed
pubmed-article:18784242pubmed:affiliationDivision of Infectious Diseases, Emory University, Atlanta, Georgia, USA. frs7@cdc.govlld:pubmed
pubmed-article:18784242pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:18784242pubmed:publicationTypeResearch Support, Non-U.S. Gov'tlld:pubmed