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pubmed-article:18760602 | lifeskim:mentions | umls-concept:C0036849 | lld:lifeskim |
pubmed-article:18760602 | lifeskim:mentions | umls-concept:C0220825 | lld:lifeskim |
pubmed-article:18760602 | lifeskim:mentions | umls-concept:C0205234 | lld:lifeskim |
pubmed-article:18760602 | lifeskim:mentions | umls-concept:C1442518 | lld:lifeskim |
pubmed-article:18760602 | lifeskim:mentions | umls-concept:C1709060 | lld:lifeskim |
pubmed-article:18760602 | lifeskim:mentions | umls-concept:C1552652 | lld:lifeskim |
pubmed-article:18760602 | lifeskim:mentions | umls-concept:C1552685 | lld:lifeskim |
pubmed-article:18760602 | lifeskim:mentions | umls-concept:C1705195 | lld:lifeskim |
pubmed-article:18760602 | pubmed:issue | 22 | lld:pubmed |
pubmed-article:18760602 | pubmed:dateCreated | 2008-11-10 | lld:pubmed |
pubmed-article:18760602 | pubmed:abstractText | A focused library of N-aryl l-homoserine lactones was designed around known lactone leads and evaluated for antagonistic and agonistic activity against quorum-sensing receptors in Agrobacterium tumefaciens, Pseudomonas aeruginosa, and Vibrio fischeri. Several compounds were identified with significantly heightened activities relative to the lead compounds, and new structure-activity relationships (SARs) were delineated. Notably, 4-substituted N-phenoxyacetyl and 3-substituted N-phenylpropionyl l-homoserine lactones were identified as potent antagonists of TraR and LuxR, respectively. | lld:pubmed |
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pubmed-article:18760602 | pubmed:language | eng | lld:pubmed |
pubmed-article:18760602 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
pubmed-article:18760602 | pubmed:citationSubset | IM | lld:pubmed |
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pubmed-article:18760602 | pubmed:status | MEDLINE | lld:pubmed |
pubmed-article:18760602 | pubmed:month | Nov | lld:pubmed |
pubmed-article:18760602 | pubmed:issn | 1464-3405 | lld:pubmed |
pubmed-article:18760602 | pubmed:author | pubmed-author:BlackwellHele... | lld:pubmed |
pubmed-article:18760602 | pubmed:author | pubmed-author:GeskeGrant... | lld:pubmed |
pubmed-article:18760602 | pubmed:author | pubmed-author:MattmannMargr... | lld:pubmed |
pubmed-article:18760602 | pubmed:issnType | Electronic | lld:pubmed |
pubmed-article:18760602 | pubmed:day | 15 | lld:pubmed |
pubmed-article:18760602 | pubmed:volume | 18 | lld:pubmed |
pubmed-article:18760602 | pubmed:owner | NLM | lld:pubmed |
pubmed-article:18760602 | pubmed:authorsComplete | Y | lld:pubmed |
pubmed-article:18760602 | pubmed:pagination | 5978-81 | lld:pubmed |
pubmed-article:18760602 | pubmed:dateRevised | 2011-11-17 | lld:pubmed |
pubmed-article:18760602 | pubmed:meshHeading | pubmed-meshheading:18760602... | lld:pubmed |
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pubmed-article:18760602 | pubmed:year | 2008 | lld:pubmed |
pubmed-article:18760602 | pubmed:articleTitle | Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators. | lld:pubmed |
pubmed-article:18760602 | pubmed:affiliation | Department of Chemistry, University of Wisconsin-Madison, 1101 University Avenue, Madison, WI 53706-1322, USA. | lld:pubmed |
pubmed-article:18760602 | pubmed:publicationType | Journal Article | lld:pubmed |
pubmed-article:18760602 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
pubmed-article:18760602 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
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