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pubmed-article:18757263pubmed:abstractTextWe observed 2 cases of Pneumocystis carinii pneumonia (PCP) occurring in HIV-negative patients during treatment with dose-dense chemotherapy with doxorubicin/cyclophosphamide (AC) followed by paclitaxel (T). These represent the first case reports of PCP occurring during dose-dense chemotherapy for breast cancer. Because lymphocyte depletion is thought to predispose patients to PCP, we explored whether the shortened intervals between cycles during dose-dense chemotherapy might place patients at risk for lymphocyte depletion and thereby a potentially increased risk of opportunistic infection.lld:pubmed
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pubmed-article:18757263pubmed:articleTitleLymphopenia associated with adjuvant anthracycline/ taxane regimens.lld:pubmed
pubmed-article:18757263pubmed:affiliationDepartment of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA. stolaney@partners.orglld:pubmed
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