Linked Life Data

18755866

Source:http://linkedlifedata.com/resource/pubmed/id/18755866

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pubmed-article:18755866pubmed:abstractTextWe describe a female Japanese patient with concomitant hypocomplementemic urticarial vasculitis, Jaccoud's arthropathy and valvular heart disease. In 1996, she developed arthritis with swelling of both proximal interphalangeal joints and urticarial vasculitis on both arms that was resolved by administration of glucocorticoid (prednisolone 30 mg/day). Tests for antineutrophil cytoplasmic antibodies, antinuclear antibody and rheumatoid factor gave negative results. The findings of a skin biopsy examination were consistent with 'leukocytoclastic vasculitis'. During 10 years of observation, the patient manifested polyarthritis leading to progressive deformity of the joints of the hands and feet (without loss of cartilage or erosion of bone), persistent urticaria exacerbated by cold and accompanied by hypocomplementemia and progressive cardiac valvular disease with mitral valve regurgitation. There are only three reports described previously documenting five patients with this rare combination of manifestations.lld:pubmed
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pubmed-article:18755866pubmed:dateRevised2009-11-19lld:pubmed
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pubmed-article:18755866pubmed:articleTitleHypocomplementemic urticarial vasculitis with Jaccoud's arthropathy and valvular heart disease: case report and review of the literature.lld:pubmed
pubmed-article:18755866pubmed:affiliationDepartment of Rheumatology and Internal Medicine, Juntendo University, Tokyo, Japan. amano@med.juntendo.ac.jplld:pubmed
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