pubmed-article:1872118 | pubmed:abstractText | Oxytocin has been shown to advance gonadotropin secretion in pro-estrus rats. The effects that oxytocin-induced changes have on the ovary were investigated in this study. Oxytocin administered to rats at proestrus 09.00 h, 10.00 h and 11.00 h advanced follicular growth, progesterone secretion, and the time of ovulation. However, both treated and control groups of rats ovulated similar numbers of oocytes and the oocytes released were of similar fertility. Because oxytocin has been shown to induce early LH and FSH release the effects of oxytocin administration on the ovary were possibly an indirect action involving the pituitary. The results of this investigation indicate that exogenous oxytocin alters the timing but not the fertility of periovulatory events. | lld:pubmed |