| pubmed-article:18715851 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18715851 | lifeskim:mentions | umls-concept:C0021294 | lld:lifeskim |
| pubmed-article:18715851 | lifeskim:mentions | umls-concept:C0001627 | lld:lifeskim |
| pubmed-article:18715851 | lifeskim:mentions | umls-concept:C0045010 | lld:lifeskim |
| pubmed-article:18715851 | lifeskim:mentions | umls-concept:C0220908 | lld:lifeskim |
| pubmed-article:18715851 | lifeskim:mentions | umls-concept:C0456081 | lld:lifeskim |
| pubmed-article:18715851 | lifeskim:mentions | umls-concept:C1552081 | lld:lifeskim |
| pubmed-article:18715851 | lifeskim:mentions | umls-concept:C0205202 | lld:lifeskim |
| pubmed-article:18715851 | lifeskim:mentions | umls-concept:C0042295 | lld:lifeskim |
| pubmed-article:18715851 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:18715851 | pubmed:dateCreated | 2008-8-21 | lld:pubmed |
| pubmed-article:18715851 | pubmed:abstractText | This study investigated the use of corrected 17-alpha-hydroxyprogesterone (17-OHP) values to detect congenital adrenal hyperplasia (CAH) in newborn infants. 17-OHP concentrations in blood spots from 913 neonates were measured using a neonatal screening test. A prematurity index was calculated using a scoring system based on gestational age and birth weight. Blood spot 17-OHP concentrations divided by the sum of prematurity scores were defined as the corrected 17-OHP values. Preterm infants (<30 wk) and low birth weight infants (<1.0 kg) showed 3.9- and 3.8-fold higher blood spot 17-OHP concentrations than normal full term infants. However, no significant differences were observed in the corrected 17-OHP values between the groups. Blood spot 17-OHP levels yielded significant correlations with the prematurity index (r = 0.42, p <0.05). Positive results for CAH were obtained in 9.5% (n = 53) and 2.0% (n = 11) of 556 premature infants by the cutoffs of blood spot 17-OHP (>15.0 ng/ml) and corrected 17-OHP values (>13.0 ng/ml), respectively. Of the 53 positive subjects, 39 (73.6%) converted to negative after 1 to 5 mo without treatment. In summary, blood spot 17-OHP levels are influenced by the prematurity of newborns. Use of corrected 17-OHP values provide limited but helpful information in screening for CAH by reducing the rate of false-positive results, especially in premature infants. | lld:pubmed |
| pubmed-article:18715851 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18715851 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18715851 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18715851 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18715851 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18715851 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18715851 | pubmed:issn | 1550-8080 | lld:pubmed |
| pubmed-article:18715851 | pubmed:author | pubmed-author:LeeMoon HeeMH | lld:pubmed |
| pubmed-article:18715851 | pubmed:author | pubmed-author:ChoiJong... | lld:pubmed |
| pubmed-article:18715851 | pubmed:author | pubmed-author:LeeJi EunJE | lld:pubmed |
| pubmed-article:18715851 | pubmed:author | pubmed-author:MoonYeonsookY | lld:pubmed |
| pubmed-article:18715851 | pubmed:author | pubmed-author:JunYong... | lld:pubmed |
| pubmed-article:18715851 | pubmed:author | pubmed-author:OhKyung IlKI | lld:pubmed |
| pubmed-article:18715851 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18715851 | pubmed:volume | 38 | lld:pubmed |
| pubmed-article:18715851 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18715851 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18715851 | pubmed:pagination | 235-40 | lld:pubmed |
| pubmed-article:18715851 | pubmed:meshHeading | pubmed-meshheading:18715851... | lld:pubmed |
| pubmed-article:18715851 | pubmed:meshHeading | pubmed-meshheading:18715851... | lld:pubmed |
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| pubmed-article:18715851 | pubmed:meshHeading | pubmed-meshheading:18715851... | lld:pubmed |
| pubmed-article:18715851 | pubmed:meshHeading | pubmed-meshheading:18715851... | lld:pubmed |
| pubmed-article:18715851 | pubmed:meshHeading | pubmed-meshheading:18715851... | lld:pubmed |
| pubmed-article:18715851 | pubmed:meshHeading | pubmed-meshheading:18715851... | lld:pubmed |
| pubmed-article:18715851 | pubmed:meshHeading | pubmed-meshheading:18715851... | lld:pubmed |
| pubmed-article:18715851 | pubmed:meshHeading | pubmed-meshheading:18715851... | lld:pubmed |
| pubmed-article:18715851 | pubmed:meshHeading | pubmed-meshheading:18715851... | lld:pubmed |
| pubmed-article:18715851 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18715851 | pubmed:articleTitle | Corrected 17-alpha-hydroxyprogesterone values adjusted by a scoring system for screening congenital adrenal hyperplasia in premature infants. | lld:pubmed |
| pubmed-article:18715851 | pubmed:affiliation | Departments of Pediatrics, College of Medicine, Inha University, Incheon, South Korea. | lld:pubmed |
| pubmed-article:18715851 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18715851 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | pubmed:referesTo | pubmed-article:18715851 | lld:pubmed |
