| pubmed-article:18715736 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18715736 | lifeskim:mentions | umls-concept:C0343375 | lld:lifeskim |
| pubmed-article:18715736 | lifeskim:mentions | umls-concept:C0039593 | lld:lifeskim |
| pubmed-article:18715736 | lifeskim:mentions | umls-concept:C1441717 | lld:lifeskim |
| pubmed-article:18715736 | lifeskim:mentions | umls-concept:C0037633 | lld:lifeskim |
| pubmed-article:18715736 | lifeskim:mentions | umls-concept:C1382100 | lld:lifeskim |
| pubmed-article:18715736 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:18715736 | pubmed:dateCreated | 2008-9-22 | lld:pubmed |
| pubmed-article:18715736 | pubmed:abstractText | We described a 5-min colorimetric test for paratyphoid A fever, which detects anti-Salmonella O2 antibodies by inhibiting the binding between 2 types of reagent particles. This test (TUBEX-PA) is based on that (TUBEX-TF) used for typhoid fever, which detects anti-O9 antibodies. TUBEX-PA showed a sensitivity of 81.0% (47/58 culture-confirmed patients) to 93.3% (14/15) and was 98.1% (52/53) specific for healthy subjects. However, TUBEX-PA also detected 50% (7/14) to 81.8% (9/11) of typhoid patients, and conversely, TUBEX-TF detected 46.7% (7/15) to 73.3% (11/15) of paratyphoid A cases. This cross-detection could be abrogated in both tests by adding a blocker (heterologous antigen) to remove the antibodies responsible, which presumably bind to a common antigen (O12) located close to O2 and O9. The presence of anti-O12 antibodies in typhoid (9/12 or 75.0% sensitive) and paratyphoid A (22/33 or 66.7%) patients was demonstrated directly using a prototypic TUBEX test designed specifically to detect these antibodies. Thus, using TUBEX-PA and TUBEX-TF together can increase the diagnostic accuracy of detecting both typhoid and paratyphoid A fever, while the further use of differential tests allows possible immediate discrimination between these diseases. | lld:pubmed |
| pubmed-article:18715736 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18715736 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18715736 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18715736 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18715736 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18715736 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18715736 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18715736 | pubmed:month | Oct | lld:pubmed |
| pubmed-article:18715736 | pubmed:issn | 0732-8893 | lld:pubmed |
| pubmed-article:18715736 | pubmed:author | pubmed-author:LimPak... | lld:pubmed |
| pubmed-article:18715736 | pubmed:author | pubmed-author:MaChun HungCH | lld:pubmed |
| pubmed-article:18715736 | pubmed:author | pubmed-author:LeungDanny... | lld:pubmed |
| pubmed-article:18715736 | pubmed:author | pubmed-author:TamFrankie... | lld:pubmed |
| pubmed-article:18715736 | pubmed:author | pubmed-author:DongBaiqingB | lld:pubmed |
| pubmed-article:18715736 | pubmed:author | pubmed-author:WangMingliuM | lld:pubmed |
| pubmed-article:18715736 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18715736 | pubmed:volume | 62 | lld:pubmed |
| pubmed-article:18715736 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18715736 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18715736 | pubmed:pagination | 142-50 | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
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| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:meshHeading | pubmed-meshheading:18715736... | lld:pubmed |
| pubmed-article:18715736 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18715736 | pubmed:articleTitle | New rapid test for paratyphoid a fever: usefulness, cross-detection, and solution. | lld:pubmed |
| pubmed-article:18715736 | pubmed:affiliation | Clinical Immunology Unit, The Chinese University of Hong Kong, Prince of Wales Hospital, Shatin, New Territories, Hong Kong. | lld:pubmed |
| pubmed-article:18715736 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18715736 | pubmed:publicationType | Evaluation Studies | lld:pubmed |
