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pubmed-article:18701294pubmed:abstractTextRadiation-induced secondary malignant neoplasms in central nervous system tumor survivors have become a problem of increasing concern over the last 20 years because of rare but serious and potentially fatal complications. Herein, we report the case of a 28-year-old man who presented with a left fronto-temporal intra- and extra-cranial tumor with intra-tumor bleeding at the site of previous radiotherapy in May 1991. He underwent craniotomy with gross total removal of the tumor and surrounding hematoma in August 2005. The tumor was a high-grade malignant myxofibrosarcoma (Fédération Nationale des Centres de Lutte Contre le Cancer Grade III [out of III]). Radiation-induced malignant myxofibrosarcoma with tumor bleeding is an infrequent complication of radiotherapy. Although rare, it should always be kept in mind with regards to the differential diagnosis of a lesion that develops several years after radiation therapy. Also, follow-up of patients that have undergone radiation therapy should be long-term.lld:pubmed
pubmed-article:18701294pubmed:languageenglld:pubmed
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pubmed-article:18701294pubmed:authorpubmed-author:ChioChung-Chi...lld:pubmed
pubmed-article:18701294pubmed:authorpubmed-author:KuoJinn-RungJ...lld:pubmed
pubmed-article:18701294pubmed:authorpubmed-author:WangChe-Chuan...lld:pubmed
pubmed-article:18701294pubmed:authorpubmed-author:LinKao-ChangK...lld:pubmed
pubmed-article:18701294pubmed:authorpubmed-author:ChuYueh-HsinY...lld:pubmed
pubmed-article:18701294pubmed:authorpubmed-author:ChuangShin-Su...lld:pubmed
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pubmed-article:18701294pubmed:volume15lld:pubmed
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pubmed-article:18701294pubmed:pagination1151-4lld:pubmed
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pubmed-article:18701294pubmed:year2008lld:pubmed
pubmed-article:18701294pubmed:articleTitleRadiation-induced intra- and extra-cranial high-grade myxofibrosarcoma with tumor bleeding.lld:pubmed
pubmed-article:18701294pubmed:affiliationDepartment of Neurosurgery, Chi-Mei Medical Center, #901 Chung Hwa Road, Yung Kang City, Tainan, Taiwan 710.lld:pubmed
pubmed-article:18701294pubmed:publicationTypeJournal Articlelld:pubmed
pubmed-article:18701294pubmed:publicationTypeCase Reportslld:pubmed