| pubmed-article:18681480 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18681480 | lifeskim:mentions | umls-concept:C0002062 | lld:lifeskim |
| pubmed-article:18681480 | lifeskim:mentions | umls-concept:C1073345 | lld:lifeskim |
| pubmed-article:18681480 | pubmed:issue | 8 | lld:pubmed |
| pubmed-article:18681480 | pubmed:dateCreated | 2008-8-25 | lld:pubmed |
| pubmed-article:18681480 | pubmed:abstractText | The bioassay-guided phytochemical investigation of Sarcococca hookeriana with respect to cholinesterase inhibitory properties has yielded two new 5alpha-pregnane-type steroidal alkaloids, hookerianamides J (1) and K (2), along with eight known compounds (3-10). The structures of 1 and 2 were elucidated by spectroscopic methods. These compounds displayed good to moderate activities in vitro against the enzymes acetylcholinesterase (IC 50 8.1-48.5 microM) and butyrylcholinesterase (IC 50 0.4-4.0 microM). Compounds 1-10 were also tested in vitro for their leishmanicidal activity against Leishmania major and for their antibacterial activities against Bacillus subtilis, Micrococcus luteus, Streptococcus faecalis, and Pseudomonas pallida. | lld:pubmed |
| pubmed-article:18681480 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18681480 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18681480 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18681480 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18681480 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18681480 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18681480 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18681480 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18681480 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18681480 | pubmed:month | Aug | lld:pubmed |
| pubmed-article:18681480 | pubmed:issn | 1520-6025 | lld:pubmed |
| pubmed-article:18681480 | pubmed:author | pubmed-author:SewaldNorbert... | lld:pubmed |
| pubmed-article:18681480 | pubmed:author | pubmed-author:ChoudharyMuha... | lld:pubmed |
| pubmed-article:18681480 | pubmed:author | pubmed-author:LentaBruno... | lld:pubmed |
| pubmed-article:18681480 | pubmed:author | pubmed-author:DevkotaKrishn... | lld:pubmed |
| pubmed-article:18681480 | pubmed:author | pubmed-author:KisangauDanie... | lld:pubmed |
| pubmed-article:18681480 | pubmed:author | pubmed-author:Samreen | lld:pubmed |
| pubmed-article:18681480 | pubmed:author | pubmed-author:NazQamarQ | lld:pubmed |
| pubmed-article:18681480 | pubmed:author | pubmed-author:WansiJean DJD | lld:pubmed |
| pubmed-article:18681480 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18681480 | pubmed:volume | 71 | lld:pubmed |
| pubmed-article:18681480 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18681480 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18681480 | pubmed:pagination | 1481-4 | lld:pubmed |
| pubmed-article:18681480 | pubmed:meshHeading | pubmed-meshheading:18681480... | lld:pubmed |
| pubmed-article:18681480 | pubmed:meshHeading | pubmed-meshheading:18681480... | lld:pubmed |
| pubmed-article:18681480 | pubmed:meshHeading | pubmed-meshheading:18681480... | lld:pubmed |
| pubmed-article:18681480 | pubmed:meshHeading | pubmed-meshheading:18681480... | lld:pubmed |
| pubmed-article:18681480 | pubmed:meshHeading | pubmed-meshheading:18681480... | lld:pubmed |
| pubmed-article:18681480 | pubmed:meshHeading | pubmed-meshheading:18681480... | lld:pubmed |
| pubmed-article:18681480 | pubmed:meshHeading | pubmed-meshheading:18681480... | lld:pubmed |
| pubmed-article:18681480 | pubmed:meshHeading | pubmed-meshheading:18681480... | lld:pubmed |
| pubmed-article:18681480 | pubmed:meshHeading | pubmed-meshheading:18681480... | lld:pubmed |
| pubmed-article:18681480 | pubmed:meshHeading | pubmed-meshheading:18681480... | lld:pubmed |
| pubmed-article:18681480 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18681480 | pubmed:articleTitle | Bioactive 5alpha-pregnane-type steroidal alkaloids from Sarcococca hookeriana. | lld:pubmed |
| pubmed-article:18681480 | pubmed:affiliation | Department of Chemistry, Organic and Bioorganic Chemistry, Bielefeld University, P.O. Box 100131, 33501 Bielefeld, Germany. devkotakpd@yahoo.com | lld:pubmed |
| pubmed-article:18681480 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18681480 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:18681480 | lld:chembl |
