| pubmed-article:18676148 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C0039771 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C0032659 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C0034721 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C0034693 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C0019564 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C0220781 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C0038477 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C1883254 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C1533691 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C2603343 | lld:lifeskim |
| pubmed-article:18676148 | lifeskim:mentions | umls-concept:C0243071 | lld:lifeskim |
| pubmed-article:18676148 | pubmed:issue | 17 | lld:pubmed |
| pubmed-article:18676148 | pubmed:dateCreated | 2008-9-4 | lld:pubmed |
| pubmed-article:18676148 | pubmed:abstractText | We synthesized several theophylline analogs and tested the hypothesis that these compounds may be nootropic or cognitive enhancers by examining their effects on evoked population spikes recorded extracellularly in the CA1 region of the rat hippocampus. Whereas the length of the carbon chain on N7 had no effect, different size of the terminal lactam ring strongly influenced neuroactivity. Our results suggest that hexahydroazepin-2-one analogs have potential for further development as cognitive enhancers. | lld:pubmed |
| pubmed-article:18676148 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18676148 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18676148 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18676148 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18676148 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18676148 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18676148 | pubmed:month | Sep | lld:pubmed |
| pubmed-article:18676148 | pubmed:issn | 1464-3391 | lld:pubmed |
| pubmed-article:18676148 | pubmed:author | pubmed-author:ForemanR JRJ | lld:pubmed |
| pubmed-article:18676148 | pubmed:author | pubmed-author:NovotnýLadisl... | lld:pubmed |
| pubmed-article:18676148 | pubmed:author | pubmed-author:MarekRadekR | lld:pubmed |
| pubmed-article:18676148 | pubmed:author | pubmed-author:Ananthalakshm... | lld:pubmed |
| pubmed-article:18676148 | pubmed:author | pubmed-author:BartlTomásT | lld:pubmed |
| pubmed-article:18676148 | pubmed:author | pubmed-author:AzizaMohammed... | lld:pubmed |
| pubmed-article:18676148 | pubmed:author | pubmed-author:BenesLudekL | lld:pubmed |
| pubmed-article:18676148 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18676148 | pubmed:day | 1 | lld:pubmed |
| pubmed-article:18676148 | pubmed:volume | 16 | lld:pubmed |
| pubmed-article:18676148 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18676148 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18676148 | pubmed:pagination | 8142-50 | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
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| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
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| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:meshHeading | pubmed-meshheading:18676148... | lld:pubmed |
| pubmed-article:18676148 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18676148 | pubmed:articleTitle | Synthesis and structure-activity relationship studies of theophylline analogs on population responses in the rat hippocampus in vitro. | lld:pubmed |
| pubmed-article:18676148 | pubmed:affiliation | Department of Applied Therapeutics, Faculty of Pharmacy, Kuwait University, P.O. Box 24923, Safat 13110, Kuwait. | lld:pubmed |
| pubmed-article:18676148 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18676148 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
| http://linkedlifedata.com/r... | http://linkedlifedata.com/r... | pubmed-article:18676148 | lld:chembl |
