| pubmed-article:186636 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:186636 | lifeskim:mentions | umls-concept:C0026626 | lld:lifeskim |
| pubmed-article:186636 | lifeskim:mentions | umls-concept:C1708726 | lld:lifeskim |
| pubmed-article:186636 | lifeskim:mentions | umls-concept:C0314603 | lld:lifeskim |
| pubmed-article:186636 | lifeskim:mentions | umls-concept:C0040671 | lld:lifeskim |
| pubmed-article:186636 | lifeskim:mentions | umls-concept:C1514468 | lld:lifeskim |
| pubmed-article:186636 | lifeskim:mentions | umls-concept:C0683598 | lld:lifeskim |
| pubmed-article:186636 | lifeskim:mentions | umls-concept:C0332120 | lld:lifeskim |
| pubmed-article:186636 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:186636 | pubmed:dateCreated | 1977-1-25 | lld:pubmed |
| pubmed-article:186636 | pubmed:abstractText | Extracts of mouse cells have been shown to transfer to N- or B-trophic host range types of mouse leukemia viruses. The genetic specificity of the inhibition was tested in two ways: (i) by correlating the Fv-1 genotype of a number of mouse strains with the restriction-transferring activity of extracts of the respective embryo cell cultures, and (ii) by correlating the Fv-1 genotype of BLC3F2 (C57BL/6 female [Fv-1bb] by C3H male [Fv-1nn] parental strains) mouse embryos, which segregate the Fv-1 alleles in a 12:1 ratio, with the inhibitor activity of extracts of the cells from each embryo. Five independent matings, totaling 45 individual embryos, were tested. Each embryo was cultured, and the Fv-1 genotype was determined independently by titration of N- and B-tropic viruses; the extracts of replicate secondary cultures were tested for their effect on infection of permissive cells by N- and B-tropic viruses. The specific-restriction-transferring activity of the embryos was found to segregate with the appropriate Fv-1 genotype. These res-lts confirm the suggestion that the inhibitor of the leukemia virus host range types in the cellular extracts is a product of the Fv-1 locus. | lld:pubmed |
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| pubmed-article:186636 | pubmed:language | eng | lld:pubmed |
| pubmed-article:186636 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:186636 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:186636 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:186636 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:186636 | pubmed:month | Dec | lld:pubmed |
| pubmed-article:186636 | pubmed:issn | 0022-538X | lld:pubmed |
| pubmed-article:186636 | pubmed:author | pubmed-author:BrownAA | lld:pubmed |
| pubmed-article:186636 | pubmed:author | pubmed-author:YangW KWK | lld:pubmed |
| pubmed-article:186636 | pubmed:author | pubmed-author:TennantR WRW | lld:pubmed |
| pubmed-article:186636 | pubmed:author | pubmed-author:OttenJ AJA | lld:pubmed |
| pubmed-article:186636 | pubmed:author | pubmed-author:SchluterBB | lld:pubmed |
| pubmed-article:186636 | pubmed:author | pubmed-author:MyerF EFE | lld:pubmed |
| pubmed-article:186636 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:186636 | pubmed:volume | 20 | lld:pubmed |
| pubmed-article:186636 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:186636 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:186636 | pubmed:pagination | 589-96 | lld:pubmed |
| pubmed-article:186636 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:186636 | pubmed:meshHeading | pubmed-meshheading:186636-G... | lld:pubmed |
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| pubmed-article:186636 | pubmed:meshHeading | pubmed-meshheading:186636-M... | lld:pubmed |
| pubmed-article:186636 | pubmed:year | 1976 | lld:pubmed |
| pubmed-article:186636 | pubmed:articleTitle | Genetic evidence for a product of the Fv-1 locus that transfers resistance to mouse leukemia viruses. | lld:pubmed |
| pubmed-article:186636 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:186636 | pubmed:publicationType | Research Support, U.S. Gov't, P.H.S. | lld:pubmed |
| pubmed-article:186636 | pubmed:publicationType | Research Support, U.S. Gov't, Non-P.H.S. | lld:pubmed |
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