| pubmed-article:18657881 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C0001675 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C0037313 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C1704632 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C0871261 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C2911692 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C1706817 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C1444748 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C0376249 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C2346753 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C0205132 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C1705241 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C0439097 | lld:lifeskim |
| pubmed-article:18657881 | lifeskim:mentions | umls-concept:C1547348 | lld:lifeskim |
| pubmed-article:18657881 | pubmed:issue | 5 | lld:pubmed |
| pubmed-article:18657881 | pubmed:dateCreated | 2010-3-19 | lld:pubmed |
| pubmed-article:18657881 | pubmed:abstractText | Aging is associated with many changes in sleep, with one of the most prominent being a reduction in slow wave sleep. Traditional measures of this phenomenon rely on spontaneous activity and typically confound the incidence and amplitude of delta waves. The measurement of evoked K-complexes during sleep, enable separate assessment of incidence and amplitude taken from the averaged K-complex waveform. The present study describes data from 70 normal healthy men and women aged between 19 and 78 years. K-Complexes were evoked using short auditory tones and recorded from a midline array of scalp sites. Significant reductions with age were seen in the amplitude of the N550 component of the averaged waveform, which represents the amplitude of the K-complex, with linear regression analysis indicating approximately 50% of the variance was due to age. Smaller, yet still significant reductions were seen in the ability to elicit K-complexes. The data highlight the utility of evoked K-complexes as a sensitive marker of brain aging in men and women. | lld:pubmed |
| pubmed-article:18657881 | pubmed:grant | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18657881 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18657881 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18657881 | pubmed:citationSubset | IM | lld:pubmed |
| pubmed-article:18657881 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18657881 | pubmed:month | May | lld:pubmed |
| pubmed-article:18657881 | pubmed:issn | 1558-1497 | lld:pubmed |
| pubmed-article:18657881 | pubmed:author | pubmed-author:BakerFiona... | lld:pubmed |
| pubmed-article:18657881 | pubmed:author | pubmed-author:TrinderJohnJ | lld:pubmed |
| pubmed-article:18657881 | pubmed:author | pubmed-author:PadillaMayraM | lld:pubmed |
| pubmed-article:18657881 | pubmed:author | pubmed-author:ColrainIan... | lld:pubmed |
| pubmed-article:18657881 | pubmed:author | pubmed-author:NicholasChris... | lld:pubmed |
| pubmed-article:18657881 | pubmed:author | pubmed-author:CrowleyKate... | lld:pubmed |
| pubmed-article:18657881 | pubmed:author | pubmed-author:AfifiLamiaL | lld:pubmed |
| pubmed-article:18657881 | pubmed:author | pubmed-author:TurlingtonSha... | lld:pubmed |
| pubmed-article:18657881 | pubmed:copyrightInfo | (c) 2008 Elsevier Inc. All rights reserved. | lld:pubmed |
| pubmed-article:18657881 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18657881 | pubmed:volume | 31 | lld:pubmed |
| pubmed-article:18657881 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18657881 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18657881 | pubmed:pagination | 874-83 | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:meshHeading | pubmed-meshheading:18657881... | lld:pubmed |
| pubmed-article:18657881 | pubmed:year | 2010 | lld:pubmed |
| pubmed-article:18657881 | pubmed:articleTitle | Sleep evoked delta frequency responses show a linear decline in amplitude across the adult lifespan. | lld:pubmed |
| pubmed-article:18657881 | pubmed:affiliation | Center for Health Sciences, SRI International, Menlo Park, CA 94025, USA. ian.colrain@sri.com | lld:pubmed |
| pubmed-article:18657881 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18657881 | pubmed:publicationType | Research Support, N.I.H., Extramural | lld:pubmed |
