| pubmed-article:18650461 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18650461 | lifeskim:mentions | umls-concept:C0086418 | lld:lifeskim |
| pubmed-article:18650461 | lifeskim:mentions | umls-concept:C0022688 | lld:lifeskim |
| pubmed-article:18650461 | pubmed:issue | 3 | lld:pubmed |
| pubmed-article:18650461 | pubmed:dateCreated | 2008-7-24 | lld:pubmed |
| pubmed-article:18650461 | pubmed:abstractText | Natural killer (NK) cells were discovered more than 30 years ago. NK cells are large granular lymphocytes that belong to the innate immune system because unlike T or B lymphocytes of the adaptive or antigen-specific immune system, NK cells do not rearrange T-cell receptor or immunoglobulin genes from their germline configuration. During the past 2 decades there has been a substantial gain in our understanding of what and how NK-cells "see," lending important insights into their functions and purpose in normal immune surveillance. The most recent discoveries in NK-cell receptor biology have fueled translational research that has led to remarkable results in treating human malignancy. | lld:pubmed |
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