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pubmed-article:18650157pubmed:abstractTextTrastuzumab combined with cytotoxic agents presents encouraging results in metastatic breast cancer (MBC), but cardiac toxicity limits some combinations. The synergism shown with trastuzumab and the favorable tolerability profile of vinorelbine provided the rationale for investigating this combination.lld:pubmed
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pubmed-article:18650157pubmed:articleTitleA phase II study of weekly vinorelbine and trastuzumab in patients with HER2-positive metastatic breast cancer.lld:pubmed
pubmed-article:18650157pubmed:affiliationServicio de Oncología Médica, Hospital Juan Ramón Jiménez, Huelva, Spain. juanbayo@yahoo.eslld:pubmed
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