Linked Life Data

18620382

Source:http://linkedlifedata.com/resource/pubmed/id/18620382

Statements in which the resource exists.
SubjectPredicateObjectContext
pubmed-article:18620382rdf:typepubmed:Citationlld:pubmed
pubmed-article:18620382lifeskim:mentionsumls-concept:C0148199lld:lifeskim
pubmed-article:18620382lifeskim:mentionsumls-concept:C1831796lld:lifeskim
pubmed-article:18620382lifeskim:mentionsumls-concept:C1999216lld:lifeskim
pubmed-article:18620382lifeskim:mentionsumls-concept:C0679622lld:lifeskim
pubmed-article:18620382lifeskim:mentionsumls-concept:C1880355lld:lifeskim
pubmed-article:18620382lifeskim:mentionsumls-concept:C0205314lld:lifeskim
pubmed-article:18620382pubmed:issue15lld:pubmed
pubmed-article:18620382pubmed:dateCreated2008-8-7lld:pubmed
pubmed-article:18620382pubmed:abstractTextInhibition of the vascular endothelial growth factor (VEGF) signaling pathway has emerged as one of the most promising new approaches for cancer therapy. We describe herein the key steps starting from an initial screening hit leading to the discovery of pazopanib, N(4)-(2,3-dimethyl-2H-indazol-6-yl)-N(4)-methyl-N(2)-(4-methyl-3-sulfonamidophenyl)-2,4-pyrimidinediamine, a potent pan-VEGF receptor (VEGFR) inhibitor under clinical development for renal-cell cancer and other solid tumors.lld:pubmed
pubmed-article:18620382pubmed:languageenglld:pubmed
pubmed-article:18620382pubmed:journalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18620382pubmed:citationSubsetIMlld:pubmed
pubmed-article:18620382pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18620382pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18620382pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18620382pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18620382pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18620382pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18620382pubmed:chemicalhttp://linkedlifedata.com/r...lld:pubmed
pubmed-article:18620382pubmed:statusMEDLINElld:pubmed
pubmed-article:18620382pubmed:monthAuglld:pubmed
pubmed-article:18620382pubmed:issn1520-4804lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:KumarRakeshRlld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:NolteRobert...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:WangLipingLlld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:StaffordJeffr...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:HarrisPhilip...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:KnickVictoria...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:VealJames MJMlld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:AlfanoNoraNlld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:SzewczykJerzy...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:CheungMuiMlld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:JohnsonJennif...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:HunterRobert...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:LuttrellDeird...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:TruesdaleAnne...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:Davis-WardRon...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:CrosbyRenae...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:EpperlyAndrea...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:RudolphSharon...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:HinkleKevin...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:LaudemanChris...lld:pubmed
pubmed-article:18620382pubmed:authorpubmed-author:MookRobert...lld:pubmed
pubmed-article:18620382pubmed:issnTypeElectroniclld:pubmed
pubmed-article:18620382pubmed:day14lld:pubmed
pubmed-article:18620382pubmed:volume51lld:pubmed
pubmed-article:18620382pubmed:ownerNLMlld:pubmed
pubmed-article:18620382pubmed:authorsCompleteYlld:pubmed
pubmed-article:18620382pubmed:pagination4632-40lld:pubmed
pubmed-article:18620382pubmed:dateRevised2009-11-19lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:meshHeadingpubmed-meshheading:18620382...lld:pubmed
pubmed-article:18620382pubmed:year2008lld:pubmed
pubmed-article:18620382pubmed:articleTitleDiscovery of 5-[[4-[(2,3-dimethyl-2H-indazol-6-yl)methylamino]-2-pyrimidinyl]amino]-2-methyl-benzenesulfonamide (Pazopanib), a novel and potent vascular endothelial growth factor receptor inhibitor.lld:pubmed
pubmed-article:18620382pubmed:affiliationGlaxoSmithKline, Five Moore Drive, Research Triangle Park, North Carolina 27709, USA. philip.a.harris@gsk.comlld:pubmed
pubmed-article:18620382pubmed:publicationTypeJournal Articlelld:pubmed
http://linkedlifedata.com/r...http://linkedlifedata.com/r...pubmed-article:18620382lld:chembl
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:18620382lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:18620382lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:18620382lld:pubmed
http://linkedlifedata.com/r...pubmed:referesTopubmed-article:18620382lld:pubmed