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pubmed-article:18590687pubmed:abstractTextThe liver plays a central role in lipid and glucose metabolism. Two studies in this issue (Kubota et al., 2008; Dong et al., 2008) on the insulin-signaling adaptors Irs1 and Irs2 prompt a critical reappraisal of the physiology of fasting and of the integrated control of hepatic insulin action.lld:pubmed
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pubmed-article:18590687pubmed:articleTitleThe double life of Irs.lld:pubmed
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