| pubmed-article:18587207 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18587207 | lifeskim:mentions | umls-concept:C0026447 | lld:lifeskim |
| pubmed-article:18587207 | lifeskim:mentions | umls-concept:C0015127 | lld:lifeskim |
| pubmed-article:18587207 | lifeskim:mentions | umls-concept:C0006931 | lld:lifeskim |
| pubmed-article:18587207 | lifeskim:mentions | umls-concept:C1314792 | lld:lifeskim |
| pubmed-article:18587207 | lifeskim:mentions | umls-concept:C0234422 | lld:lifeskim |
| pubmed-article:18587207 | lifeskim:mentions | umls-concept:C0343068 | lld:lifeskim |
| pubmed-article:18587207 | lifeskim:mentions | umls-concept:C0332237 | lld:lifeskim |
| pubmed-article:18587207 | lifeskim:mentions | umls-concept:C0185125 | lld:lifeskim |
| pubmed-article:18587207 | lifeskim:mentions | umls-concept:C1522168 | lld:lifeskim |
| pubmed-article:18587207 | pubmed:issue | 2 | lld:pubmed |
| pubmed-article:18587207 | pubmed:dateCreated | 2008-6-30 | lld:pubmed |
| pubmed-article:18587207 | pubmed:abstractText | Recent animal studies have demonstrated that many trigeminal ganglion neurons co-express TRPV1 and TRPA1 receptors following peripheral inflammation. In the present study, we examined whether cold receptors were sensitized by capsaicin in awake monkeys. Two monkeys were trained to detect a change in cold stimulus temperature (30 degrees C to 0.5, 1.0, 1.5 or 2.0 degrees C) applied to the facial skin. A total of 589 trials were studied, and the number of escape and hold-through trials and detection latency were measured. The number of escape trials was increased after capsaicin treatment, whereas that of hold-through trials was decreased. Detection latency was significantly decreased after capsaicin treatment. The present findings suggest that topical application of capsaicin to the facial skin induces reversible hypersensitivity to a facial cold stimulus in behaving monkeys. | lld:pubmed |
| pubmed-article:18587207 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18587207 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18587207 | pubmed:citationSubset | D | lld:pubmed |
| pubmed-article:18587207 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18587207 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18587207 | pubmed:chemical | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18587207 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18587207 | pubmed:month | Jun | lld:pubmed |
| pubmed-article:18587207 | pubmed:issn | 1343-4934 | lld:pubmed |
| pubmed-article:18587207 | pubmed:author | pubmed-author:MasudaYujiY | lld:pubmed |
| pubmed-article:18587207 | pubmed:author | pubmed-author:IwataKoichiK | lld:pubmed |
| pubmed-article:18587207 | pubmed:author | pubmed-author:TsuboiYoshiyu... | lld:pubmed |
| pubmed-article:18587207 | pubmed:author | pubmed-author:YamashitaAkik... | lld:pubmed |
| pubmed-article:18587207 | pubmed:author | pubmed-author:KondoMasahiro... | lld:pubmed |
| pubmed-article:18587207 | pubmed:author | pubmed-author:TairaMasatoM | lld:pubmed |
| pubmed-article:18587207 | pubmed:author | pubmed-author:KatoTakafumiT | lld:pubmed |
| pubmed-article:18587207 | pubmed:author | pubmed-author:KitagawaJunic... | lld:pubmed |
| pubmed-article:18587207 | pubmed:author | pubmed-author:KamoHiroshiH | lld:pubmed |
| pubmed-article:18587207 | pubmed:author | pubmed-author:KatsuyamaNaru... | lld:pubmed |
| pubmed-article:18587207 | pubmed:author | pubmed-author:HondaKuniyaK | lld:pubmed |
| pubmed-article:18587207 | pubmed:issnType | Print | lld:pubmed |
| pubmed-article:18587207 | pubmed:volume | 50 | lld:pubmed |
| pubmed-article:18587207 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18587207 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18587207 | pubmed:pagination | 175-9 | lld:pubmed |
| pubmed-article:18587207 | pubmed:dateRevised | 2008-11-21 | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:meshHeading | pubmed-meshheading:18587207... | lld:pubmed |
| pubmed-article:18587207 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18587207 | pubmed:articleTitle | Topical capsaicin application causes cold hypersensitivity in awake monkeys. | lld:pubmed |
| pubmed-article:18587207 | pubmed:affiliation | Department of Oral and Maxillofacial Surgery, Nihon University School of Dentistry, Tokyo, Japan. | lld:pubmed |
| pubmed-article:18587207 | pubmed:publicationType | Journal Article | lld:pubmed |
| pubmed-article:18587207 | pubmed:publicationType | Research Support, Non-U.S. Gov't | lld:pubmed |
