A risk haplotype of STAT4 for systemic lupus erythematosus is over-expressed, correlates with anti-dsDNA and shows additive effects with two risk alleles of IRF5.

Source:http://linkedlifedata.com/resource/pubmed/id/18579578

Hum. Mol. Genet. 2008 Sep 15 17 18 2868-76

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18579578