| pubmed-article:18575598 | rdf:type | pubmed:Citation | lld:pubmed |
| pubmed-article:18575598 | lifeskim:mentions | umls-concept:C0010592 | lld:lifeskim |
| pubmed-article:18575598 | lifeskim:mentions | umls-concept:C0030524 | lld:lifeskim |
| pubmed-article:18575598 | lifeskim:mentions | umls-concept:C0072980 | lld:lifeskim |
| pubmed-article:18575598 | lifeskim:mentions | umls-concept:C0085149 | lld:lifeskim |
| pubmed-article:18575598 | lifeskim:mentions | umls-concept:C0441472 | lld:lifeskim |
| pubmed-article:18575598 | lifeskim:mentions | umls-concept:C1883207 | lld:lifeskim |
| pubmed-article:18575598 | lifeskim:mentions | umls-concept:C0332257 | lld:lifeskim |
| pubmed-article:18575598 | pubmed:issue | 6 | lld:pubmed |
| pubmed-article:18575598 | pubmed:dateCreated | 2008-6-25 | lld:pubmed |
| pubmed-article:18575598 | pubmed:abstractText | Mycobacterium avium subspecies paratuberculosis (MAP) may be zoonotic. Recently the "immuno-modulators" methotrexate, azathioprine and 6-MP and the "anti-inflammatory" 5-ASA have been shown to inhibit MAP growth in vitro. We concluded that their most plausible mechanism of action is as antiMAP antibiotics. The "immunosuppressants" Cyclosporine A, Rapamycin and Tacrolimus (FK 506) treat a variety of "autoimmune" and "inflammatory" diseases. Rapamycin and Tacrolimus are macrolides. We hypothesized that their mode of action may simply be to inhibit MAP growth. | lld:pubmed |
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| pubmed-article:18575598 | pubmed:language | eng | lld:pubmed |
| pubmed-article:18575598 | pubmed:journal | http://linkedlifedata.com/r... | lld:pubmed |
| pubmed-article:18575598 | pubmed:citationSubset | IM | lld:pubmed |
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| pubmed-article:18575598 | pubmed:status | MEDLINE | lld:pubmed |
| pubmed-article:18575598 | pubmed:issn | 1932-6203 | lld:pubmed |
| pubmed-article:18575598 | pubmed:author | pubmed-author:GreensteinRob... | lld:pubmed |
| pubmed-article:18575598 | pubmed:author | pubmed-author:BrownSheldon... | lld:pubmed |
| pubmed-article:18575598 | pubmed:author | pubmed-author:JusteRamon... | lld:pubmed |
| pubmed-article:18575598 | pubmed:author | pubmed-author:SuLiyaL | lld:pubmed |
| pubmed-article:18575598 | pubmed:issnType | Electronic | lld:pubmed |
| pubmed-article:18575598 | pubmed:volume | 3 | lld:pubmed |
| pubmed-article:18575598 | pubmed:owner | NLM | lld:pubmed |
| pubmed-article:18575598 | pubmed:authorsComplete | Y | lld:pubmed |
| pubmed-article:18575598 | pubmed:pagination | e2496 | lld:pubmed |
| pubmed-article:18575598 | pubmed:dateRevised | 2009-11-18 | lld:pubmed |
| pubmed-article:18575598 | pubmed:meshHeading | pubmed-meshheading:18575598... | lld:pubmed |
| pubmed-article:18575598 | pubmed:meshHeading | pubmed-meshheading:18575598... | lld:pubmed |
| pubmed-article:18575598 | pubmed:meshHeading | pubmed-meshheading:18575598... | lld:pubmed |
| pubmed-article:18575598 | pubmed:meshHeading | pubmed-meshheading:18575598... | lld:pubmed |
| pubmed-article:18575598 | pubmed:meshHeading | pubmed-meshheading:18575598... | lld:pubmed |
| pubmed-article:18575598 | pubmed:meshHeading | pubmed-meshheading:18575598... | lld:pubmed |
| pubmed-article:18575598 | pubmed:meshHeading | pubmed-meshheading:18575598... | lld:pubmed |
| pubmed-article:18575598 | pubmed:year | 2008 | lld:pubmed |
| pubmed-article:18575598 | pubmed:articleTitle | On the action of cyclosporine A, rapamycin and tacrolimus on M. avium including subspecies paratuberculosis. | lld:pubmed |
| pubmed-article:18575598 | pubmed:affiliation | Department of Surgery, Veterans Affairs Medical Center, Bronx, New York, United States of America. BGAxis@aol.com | lld:pubmed |
